910297-69-7 Usage
Uses
Used in Pharmaceutical Industry:
2,2-DiMethyl-propanoic Acid [2-[[(2-AMino-5-thiazolyl)carbonyl]aMino]-3-chlorophenyl]Methyl Ester is used as an intermediate in the preparation of Dasatinib metabolite for the treatment of cancers and immune diseases. Its unique molecular structure allows it to play a crucial role in the synthesis of Dasatinib, a potent tyrosine kinase inhibitor that has been shown to be effective in treating various types of cancer, including leukemia, lymphoma, and solid tumors. Additionally, Dasatinib has also been found to have potential applications in the treatment of autoimmune diseases, such as rheumatoid arthritis and lupus, due to its ability to modulate immune cell signaling pathways.
Check Digit Verification of cas no
The CAS Registry Mumber 910297-69-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,0,2,9 and 7 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 910297-69:
(8*9)+(7*1)+(6*0)+(5*2)+(4*9)+(3*7)+(2*6)+(1*9)=167
167 % 10 = 7
So 910297-69-7 is a valid CAS Registry Number.
910297-69-7Relevant academic research and scientific papers
PROCESS FOR PREPARING N-(2-CHLORO-6-METHYLPHENYL)-2-[[6-[4-(2-HYDROXYETHYL)-1-PIPERAZINYL]-2-METHYL-4-PYRIMIDINYL]AMINO] -5-THIAZOLECARBOXAMIDE AND RELATED METABOLITES THEREOF
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Page/Page column 24; 26, (2010/11/28)
The present invention is directed to process for the preparation of metabolites as well as the parent compound of N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl] amino]-5-thiazolecarboxamide, the compound of formula (I).
'N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamides metabolites
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Page/Page column 34, (2008/06/13)
The present invention is directed to metabolites of ′N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide, the compound of formula (I), pharmaceutical compositions thereof, and to methods
