910330-79-9Relevant academic research and scientific papers
Assembly of the southern macrocyclic half of (+)-spirastrellolide a through cyclic acetal tethered ring-closing metathesis and 1,3-anti-mukaiyama-aldol
Tang, Yu,Yang, Jin-Haek,Liu, Jia,Wang, Chao-Chao,Lv, Ming-Can,Wu, Yi-Biao,Yu, Xue-Liang,Ko, Changhong,Hsung, Richard P.
, p. 565 - 598 (2013/08/23)
We describe herein details of our efforts in syntheses of A-ring and BC-ring of (+)-spirastrellolide A. While the former would constitute a facile 12-step synthetic endeavor starting from 1,5-pentanediol, the latter would showcase a cyclic acetal-tethered
Synthesis of the C1-C16 fragment of spirastrellolide A
Liu, Jia,Yang, Jin Haek,Ko, Changhong,Hsung, Richard P.
, p. 6121 - 6123 (2007/10/03)
Synthesis of the C1-C16 fragment of spirastrellolide A is described here featuring Sharpless asymmetric epoxidation, an acid promoted O-1,4-addition, and Mukaiyama 1,3-anti-aldol.
