91055-64-0

Basic information

• Product Name: 5-Pyrimidinecarbonitrile,4-amino-2-isopropyl-(7CI)
• Synonyms: 5-Pyrimidinecarbonitrile,4-amino-2-isopropyl-(7CI)
• CAS NO: 91055-64-0
• Molecular Formula: C8H10N4
• Molecular Weight: 162.1918
• Product Categories: ISOPROPYL
• Mol File: 91055-64-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-Pyrimidinecarbonitrile,4-amino-2-isopropyl-(7CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Pyrimidinecarbonitrile,4-amino-2-isopropyl-(7CI)(91055-64-0)
• EPA Substance Registry System: 5-Pyrimidinecarbonitrile,4-amino-2-isopropyl-(7CI)(91055-64-0)

Safety Data

• Hazardous Substances Data: 91055-64-0(Hazardous Substances Data)

Upstream product

• 94741-70-5 4-Amino-2-bromo-5-pyrimidinecarbonitrile 
• 77047-87-1 isopropyl zinc bromide 

Relevant articles and documents

CYCLIC AMINOMETHYL PYRIMIDINE DERIVATIVE

The present invention provides a cyclic aminomethyl pyrimidine derivative and a pharmaceutically acceptable salt thereof with high selectivity for dopamine D4 receptors, which are useful for treating a disease such as attention deficit hyperactivity disorder. Specifically, a compound of formula (1) or a pharmaceutically acceptable salt thereof is provided, wherein n and m are independently 1 or 2; Ra is C1-6 alkyl group, C3-6 cycloalkyl group, or amino group; Rb is hydrogen atom, C1-6 alkyl group or the like, provided that when Ra is amino group, then Rb is hydrogen atom; Rc1 and Rc2 are independently hydrogen atom, or C1-6 alkyl group; Rd1 and Rd2 are independently hydrogen atom, fluorine atom or the like; ring Q is an optionally-substituted pyridyl group or an optionally-substituted isoquinolyl group; and the bond having a dashed line is a single or double bond.