91064-30-1

Upstream product

• 108-77-0 1,3,5-trichloro-2,4,6-triazine 
• 583-70-0 1-bromo-2,4-dimethylbenzene 
• 108-38-3 m-xylene 

Downstream Products

• 1237-53-2 2-chloro-4,6-bis(2',4'-dimethylphenyl)-1,3,5-triazine 

Relevant academic research and scientific papers

Method for synthesizing triazine compound by Friedel-Crafts reaction micro-channel method

The invention discloses a method for synthesizing a triazine compound by a Friedel-Crafts reaction micro-channel method. The method comprises the following steps: carrying out mixing dissolving on cyanuric chloride represented by a formula (I), a compound represented by a formula (II), a Lewis acid as a catalyst and an organic solvent to obtain a reaction solution for later use; replacing and exhausting the air in a micro-channel reactor by using nitrogen, injecting the prepared reaction liquid into the micro-channel reactor through a metering pump, carrying out a Friedel-Crafts reaction, controlling the reaction temperature to be 0-120 DEG C, controlling the reaction retention time to be 10-180 minutes, and carrying out post-treatment on the reaction liquid flowing out of the micro-channel reactor to obtain the triazine compound represented by a formula (III), wherein in the formula (II) and the formula (III), the substituent R1 is hydrogen, methyl, hydroxyl, methoxy or chlorine atom,and the substituent R2 is hydrogen, methyl or hydroxyl. By adopting the micro-channel reactor, the corresponding reaction conditions are optimized, the mass transfer and heat transfer effects of thereaction are good, the reaction time is shortened, side reactions are reduced, and the yield of the target product is high.

Process for making triazine UV absorbers using lewis acids and reaction promoters

It has been now surprisingly discovered after extensive research that 2-halo-4,6-bisaryl-1,3,5-triazine can be prepared with unprecedented selectivity, efficiency, mild conditions, and in high yield by the reaction of cyanuric halide with aromatics in the presence of at least one Lewis acid and at least one reaction promoter. This reaction is also unprecedently general as a variety of aromatics can be used to produce a wide selection of 2-halo-4,6-bisaryl-1,3,5-triazines. The novel approach includes the use of the reaction promoters in combination with at least one Lewis acid under certain reaction conditions to promote the formation of 2-halo-4,6-bisaryl-1,3,5-triazine compounds from cyanuric halide. Preferably, the Lewis acids and reaction promoters are combined to form a complex. 2-Halo-4,6-bisaryl-1,3,5-triazines are key intermediates for making 2-(2-oxyaryl)-4,6-bisaryl-1,3,5-triazine class of UV absorbers.

Process for the preparation of mono- and diaryltriazines

A process for the selective preparation of 2,4-dichloro-6-aryl- or 2-chloro-4,6-diaryl-1,3,5-triazines is described, which comprises reacting a compound of formula II STR1 wherein X is a bromine or chlorine atom, and R1 and R2 are independently hydrogen or alkyl, in tetrahydrofuran with magnesium metal to form the corresponding Grignard reagent, and reacting the resultant solution with cyanuric chloride of formula III STR2 such that, if Z is --Cl, at least 1.05 mol and, if Z is a radical of formula Ib, at least 2.1 mol, of Grignard reagent is used per 1 mol of cyanuric chloride. The compounds of formula I can be used with advantage for the preparation of 2-(o-hydroxyphenyl)-4,6-diaryl-s-triazines, which are known light stabilizers for organic material.