91077-77-9Relevant articles and documents
Versatile and base-free copper-catalyzed α-arylations of aromatic ketones using diaryliodonium salts
Bouquin, Maxime,Jaroschik, Florian,Taillefer, Marc
supporting information, (2021/06/11)
A ligand and base-free copper catalyzed synthetic method for the efficient α-arylation of aromatic ketones is described. In order to avoid strong bases, ketone-derived silyl enol ethers were employed. Their reaction with diaryliodonium salts as aryl source provided the intermolecular C–C coupling displaying good functional group tolerance and requiring low catalyst loading.
Visible light-induced palladium-catalyzed ring opening β-H elimination and addition of cyclobutanone oxime esters
Xing, Wei-Long,Shang, Rui,Wang, Guang-Zu,Fu, Yao
supporting information, p. 14291 - 14294 (2019/12/02)
A palladium catalyst under visible light irradiation activates cyclobutanone oxime ester through single electron transfer to induce radical ring opening to generate hybrid cyanoalkyl Pd(i) radical species. Hybrid cyanoalkyl Pd(i) radical species can undergo either β-H elimination to deliver (E)-4-arylbut-3-enenitrile or undergo radical addition with silyl enol ether and enamide to generate δ-cyano ketones. A dual ligand system composed of two phosphine ligands is essential for the high reactivity.
Ring-Opening Diarylation of Siloxydifluorocyclopropanes by Ag(I) Catalysis: Stereoselective Construction of 2-Fluoroallylic Scaffold
Song, Xiaoning,Xu, Cong,Du, Dongxu,Zhao, Ziming,Zhu, Dongsheng,Wang, Mang
supporting information, p. 6542 - 6545 (2017/12/26)
A silver-catalyzed, defluorination ring-opening diarylation of siloxy 2,2-difluorocyclopropanes, with two arenes, to directly prepare polysubstituted 2-fluoroallylic compounds, is described. This multicomponent reaction proceeds smoothly in good stereoselectivity, which is due to a chelation-controlled addition of arenes to α-fluorinated ketone intermediate.
