91086-60-1Relevant academic research and scientific papers
Reactions of SH-substituted purine bases with glycidol
Radchenko,Ratsino
, p. 624 - 626 (2004)
The regioselectivity of S-alkylation of SH-substituted purine bases with glycidol tends to grow with decreasing temperature. A procedure was developed for epoxidation of these compounds in wet liquid ammonia. The products were tested for immunostimulating
SYNTHESIS AND SOME PROPERTIES OF 6-β-OXOALKYL(ARALKYL, HETARALKYL, CYCLOALKYL)THIOPURINES
Kochergin, P. M.,Gromov, M. Yu.,Aleksandrova, E. V.,Skachilova, S. Ya.
, p. 1335 - 1339 (2007/10/02)
The reaction of 6-purinethione with α-haloketones has given a series of new 6-β-oxoalkyl(aralkyl, hetaralkyl, cycloalkyl)thiopurines.Their alkylation in position 9 and acid hydrolysis to hypoxanthine and its 9-alkyl derivatives has been studied.The hydrolysis of the acetals of 6-formylmethylthiopurine and the oxidation of 6-(2,3-dihydroxypropyl)thiopurine leads to 6-formylmethylthiopurine, which shows a ring-chain tautomerism and exists in the form of 7-hydroxy-7,8-dihydrothiazolopurine.
