91127-30-9

Upstream product

• 15184-99-3 N,N-dimethyl-3-methoxybenzylamine 
• 79-22-1 methyl chloroformate 
• 91127-29-6 Methyl 6-<(N,N-dimethylamino)methyl>-2-methoxybenzoate 

Downstream Products

• 330194-39-3 2-(R)-(7-methoxy-2,3-dihydro-isoindol-1-one-2-ylmethyl)-4,4-diethoxy-1-(1-(S)-phenyl-ethyl)-piperidine 
• 909554-64-9 2-[3-((2S,6S)-6-{(3S,4R)-7-[(2S,6R)-6-(1-Ethoxycarbonyl-1-methyl-ethyl)-tetrahydro-pyran-2-yl]-4-hydroxy-3-methyl-6-oxo-heptyl}-tetrahydro-pyran-2-yl)-propyl]-6-methoxy-benzoic acid methyl ester 
• 909554-73-0 2-{(E)-3-[(2R,6S)-6-((S)-4-Benzyloxy-3-methyl-butyl)-tetrahydro-pyran-2-yl]-propenyl}-6-methoxy-benzoic acid methyl ester 
• 909554-62-7 (2S,6S,3'S)-2-(4-hydroxy-3-methylbutyl)-6-[3-(3-methyoxy-2-methoxycarbonylphenyl)propyl]tetrahydropyran 
• 909554-63-8 2-Methoxy-6-{3-[(2S,6S)-6-((S)-3-methyl-4-oxo-butyl)-tetrahydro-pyran-2-yl]-propyl}-benzoic acid methyl ester 
• 73177-51-2 methyl 6-(iodomethyl)-2-methoxybenzoate 
• 28281-58-5 7-methoxyisobenzofuran-1(3H)-one 
• 91127-24-1 (+/-)-(4bβ,10α)-Benzyl (8,8-ethylenedioxy)-2-methoxy-1-(methoxycarbonyl)-7-<(methoxymethyl)oxy>gibba-1,3,4a(10a)-triene-10-carboxylate 
• 73177-43-2 2,5-Dimethoxy-1-<(3'-methoxy-2'-(methoxycarbonyl)phenyl)methyl>-2,5-cyclohexadiene-1-carboxylic acid 

Relevant academic research and scientific papers

Stereoselective synthesis of the monomeric unit of SCH 351448

The monomeric unit of the macrodiolide SCH 351448 has been synthesized from three building blocks. Strategic disconnections were chosen between C21-C22 (Wittig) and C10-C11 (stereoselective aldol). The cis configuration of both 2,6-disubstituted tetrahydropyran rings was established by a stereoselective cationic reduction. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.

Studies on Gibberellin Synthesis: The Total Synthesis of Gibberellic Acid from Hydrofluorenone Intermediates

Reductive alkylation of 2,5-dimethoxybenzoic acid with benzyl iodide 15 followed by cyclodehydration furnished fluorenone 8 which was converted into gibbane 10 by means of an acid-catalyzed intramolecular cyclization procedure based on diazo ketone 21.Ben

Reductive Alkylation of 2,5-Dimethoxybenzoic Acid: A Direct Synthesis of Dihydrofluoren-2-ones

A two-operation procedure is described for the synthesis of 3,4-dihydrofluoren-2(1H)-ones from "reductive alkylation" of 2,5-dimethoxybenzoic acid with benzyl halides, followed by cyclodehydration of the adducts, with concomitant decarboxylation.