909554-64-9

Upstream product

• 42991-09-3 4-(2-methyl-1,3-dioxolan-2-yl)butanal 
• 91127-30-9 Methyl-6-(chloromethyl)-2-methoxybenzoate 
• 909554-55-8 (6S)-6-allyltetrahydropyran-2-ol 
• 610-89-9 2-acetyl-pent-4-enoic acid ethyl ester 
• 909554-66-1 (R)-7-(2-Methyl-[1,3]dioxolan-2-yl)-hept-1-en-4-ol 
• 909554-56-9 (6S)-2-acetoxy-6-allyltetrahydropyran 
• 909554-51-4 2-Methyl-2-[(2R,6S)-6-(2-oxo-propyl)-tetrahydro-pyran-2-yl]-propionic acid ethyl ester 
• 909554-63-8 2-Methoxy-6-{3-[(2S,6S)-6-((S)-3-methyl-4-oxo-butyl)-tetrahydro-pyran-2-yl]-propyl}-benzoic acid methyl ester 
• 764-59-0 hex-5-en-1-al 
• 109-49-9 5-Hexen-2-one 
• 5745-75-5 4-(2-methyl-[1,3]-dioxolan-2-yl)butan-1-ol 
• 20449-21-2 2-(but-3-en-1-yl)-2-methyl-1,3-dioxolane 
• 909554-73-0 2-{(E)-3-[(2R,6S)-6-((S)-4-Benzyloxy-3-methyl-butyl)-tetrahydro-pyran-2-yl]-propenyl}-6-methoxy-benzoic acid methyl ester 
• 909554-53-6 (2S,9R)-1-benzyloxy-2-methyl-9-tiisopropylsilyloxy-11-dodecen-5-one 

Relevant academic research and scientific papers

Stereoselective synthesis of the monomeric unit of SCH 351448

The monomeric unit of the macrodiolide SCH 351448 has been synthesized from three building blocks. Strategic disconnections were chosen between C21-C22 (Wittig) and C10-C11 (stereoselective aldol). The cis configuration of both 2,6-disubstituted tetrahydropyran rings was established by a stereoselective cationic reduction. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.