911307-89-6Relevant academic research and scientific papers
The first total synthesis of gobichelin B: A mixed-ligand siderophore of: Streptomyces sp. NRRL F-4415
Sridhar, Perali Ramu,Venkatesh,Kalesha, Shaik,Sudharani, Chalapala
, p. 3732 - 3740 (2018)
The first total synthesis of a structurally diverse mixed ligand siderophore, gobichelin B produced by Streptomyces sp. NRRL F-4415, is reported. The systematic assembly of the building blocks to synthesize Gob-B 1st half and Gob-B 2nd half and subsequent coupling of these two fragments followed by global deprotection using Pearlman's catalyst led to the isolation of gobichelin B in excellent yield and purity.
An atom-efficient direct regioselective N(τ)-allylation of histidine derivatives
Halland, Nis
, p. 2969 - 2971 (2012)
Protected N(τ)-allylhistidine has been been prepared by the first direct regioselective allylation procedure using the sterically bulky N(α)-Boc protection group to shield N(π) and thereby inducing regioselectivity. This afforded the N(τ)-allyl protected
Substrate-directed lewis-acid catalysis for peptide synthesis
Muramatsu, Wataru,Hattori, Tomohiro,Yamamoto, Hisashi
supporting information, p. 12288 - 12295 (2019/08/20)
A Lewis-acid-catalyzed method for the substrate-directed formation of peptide bonds has been developed, and this powerful approach is utilized for the new "remote" activation of carboxyl groups under solvent-free conditions. The presented method has the following advantages: (1) the high-yielding peptide synthesis uses a tantalum catalyst for any amino acids; (2) the reaction proceeds without any racemization; (3) the new substrate-directed chemical ligation using the titanium catalyst is applicable to convergent peptide synthesis. These advantages overcome some of the unresolved problems in classical peptide synthesis.
Zinc(II) tweezers containing artificial peptides mimicking the active site of phosphotriesterase: The catalyzed hydrolysis of the toxic organophosphate parathion
Ibrahim, Mohamed M.,Mersal, Gaber A.M.
experimental part, p. 1195 - 1204 (2011/12/14)
Two new ligand-containing histidine based on N,N',N"-tris(N-benzyl-l-histidinyl)tri(2-aminoethyl)amine, L1, namely N,N',N"-tris[(1S)-2-methoxy-2-oxy-1-(1-benzylimidazol-4-ylmethyl)]nitrilotriacetamide L2 and N,N',N"-tris{N-benzyl-N-[
