91133-04-9

Basic information

• Product Name: 4H-1,3-Oxazine, 5,6-dihydro-2-(4-methoxyphenyl)-
• CAS NO: 91133-04-9
• Molecular Formula: C11H13NO2
• Molecular Weight: 191.23
• Mol File: 91133-04-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4H-1,3-Oxazine, 5,6-dihydro-2-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1,3-Oxazine, 5,6-dihydro-2-(4-methoxyphenyl)-(91133-04-9)
• EPA Substance Registry System: 4H-1,3-Oxazine, 5,6-dihydro-2-(4-methoxyphenyl)-(91133-04-9)

Safety Data

• Hazardous Substances Data: 91133-04-9(Hazardous Substances Data)

Upstream product

• 100-07-2 4-methoxy-benzoyl chloride 
• 109086-77-3 2-(4'-methoxyphenyl)perhydro-1,3-oxazine 
• 72320-38-8 3-azidopropan-1-ol 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 94615-57-3 (6R,7R)-6-(4-Methoxy-phenyl)-7-phenoxy-5-oxa-1-aza-bicyclo[4.2.0]octan-8-one 

Relevant articles and documents

One-step conversion of aldehydes to oxazolines and 5,6-dihydro-4H-1,3-oxazines using 1,2- and 1,3-azido alcohols

The reactions of 1,2- and 1,3-hydroxy azides with aldehydes under acidic conditions were examined. A variety of Lewis acids were examined, of which BF3·OEt2 was found the most convenient. Trimethylsilyl ether derivatives of the alcohols could also be reacted using trimethylsilyl triflate as the promoter. Twenty-five examples that proceed in moderate to quantitative yields are reported.

Efficient oxidative conversion of aldehydes to 2-substituted oxazolines and oxazines using (diacetoxyiodo)benzene

An efficient synthesis of 2-substituted oxazolines from aldehydes and 2-amino alcohol using (diacetoxyiodo)benzene as an oxidant, is reported. (Diacetoxyiodo)benzene acts as a mild dehydrogenating agent to convert the initially formed oxazolidine from ald