91157-36-7Relevant articles and documents
Conformationally Restrained Fentanyl Analogues. 2. Synthesis and Analgetic Evaluation of Perhydro-1,6-naphthyridin-2-ones
Borne, Ronald F.,Fifer, E. Kim,Waters, I.W.
, p. 1271 - 1275 (1984)
Conformational flexibility of the N-acyl portion of fentanyl-type analgetics was restricted through the synthesis of novel perhydro-1,6-naphthyridin-2-one derivatives.Neither the cis-fused derivative (5a), the trans-fused derivative (5b), nor the enamide