Conformationally Restrained Fentanyl Analogues. 2. Synthesis and Analgetic Evaluation of Perhydro-1,6-naphthyridin-2-ones

DOI: 10.1021/jm00376a007

Source and publish data:

Journal of Medicinal Chemistry p. 1271 - 1275 (1984)

Update date:2022-08-04

Topics:

Authors:

Borne, Ronald F.

Fifer, E. Kim

Waters, I.W.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00376a007

Conformational flexibility of the N-acyl portion of fentanyl-type analgetics was restricted through the synthesis of novel perhydro-1,6-naphthyridin-2-one derivatives.Neither the cis-fused derivative (5a), the trans-fused derivative (5b), nor the enamide

Full text of DOI:10.1021/jm00376a007

Products guided by the article

Product name:Pyridine, 1,2,3,6-tetrahydro-1-(2-phenylethyl)-4-(1-pyrrolidinyl)-

Cas No:91157-36-7

R&D Labs maybe for 91157-36-7

Shanghai Yingrui Biopharma Co., Ltd

Contact:021-3358 8661*8003

Address:shanghai
Foreschem Co., Ltd

Contact:+86-533-3112891

Address:zibo
Jiangsu Dacheng Pharmaceutical and Chemical Co.,Ltd

Contact:+86-0517-87036900

Address:Chuzhou Chemical park, Huai'an, Jiangsu Province
shanghai jiuling chemical co.,ltd.

Contact:+86-21-50387295

Address:Zaozhuang Road, Pudong, Shanghai City. China
Wuhan Jadechem International Trade Co.,Ltd.

website:http://www.jadechem-intl.com

Contact:+86-27-83527060

Address:Room 502,Building C11,Software new city No.8,Huacheng Avenue,East Lake High-tech development zone,Wuhan,Hubei,China

Relevant to this article

SYNTHESES AND SPECTROSCOPIC STUDIES ON SOME PLATINUM GROUP METAL COMPLEXES WITH OXAZEPAM AS LIGAND

Doi:10.1016/0022-2860(84)87050-7
(1984)
The One-Electron Transfer Induced Photocycloreversion of Stilbazolium Cyclodimers

Doi:10.1246/bcsj.71.419
(1998)
Total Synthesis of a Partial Structure from Arabinogalactan and Its Application for Allergy Prevention

Doi:10.1002/chem.202002287
(2021)
Trigonal-bipyramidal geometry induced by an external water ligand in a sterically hindered iron salen complex, related to the active site of protocatechuate 3,4-dioxygenase

Doi:10.1021/ic060650p
(2006)
Synthesis of Lewis A trisaccharide analogues in which d-glucose and l-rhamnose replace d-galactose and l-fucose, respectively

Doi:10.1016/j.carres.2006.07.006
(2006)
Towards a better understanding of photo-excited spin alignment processes using silole diradicals

Doi:10.1039/b606593g
(2006)

Article Doi