91203-74-6

Basic information

• Product Name: Benzyl 4-(benzyloxy)-3-methoxybenzoate
• Synonyms: Benzyl 4-(benzyloxy)-3-methoxybenzoate
• CAS NO: 91203-74-6
• Molecular Formula: C₂₂H₂₀O₄
• Molecular Weight: 348.396
• Mol File: 91203-74-6.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 500.6 °C at 760 mmHg
• Flash Point: 219 °C
• Appearance: /
• Density: 1.174 g/cm³
• Vapor Pressure: 3.73E-10mmHg at 25°C
• Refractive Index: 1.591
• CAS DataBase Reference: Benzyl 4-(benzyloxy)-3-methoxybenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Benzyl 4-(benzyloxy)-3-methoxybenzoate(91203-74-6)
• EPA Substance Registry System: Benzyl 4-(benzyloxy)-3-methoxybenzoate(91203-74-6)

Safety Data

• Hazardous Substances Data: 91203-74-6(Hazardous Substances Data)

Usage

General Description

Benzyl 4-(benzyloxy)-3-methoxybenzoate is an organic compound that belongs to the class of benzoic acid esters. It is a white crystalline solid, commonly used in the synthesis of various pharmaceuticals and agrochemicals. The compound is known for its potential antiviral and anticancer properties, making it a valuable ingredient in the development of new drugs. It is also used as a flavoring agent in the food industry. Additionally, benzyl 4-(benzyloxy)-3-methoxybenzoate has been studied for its potential role in the field of materials science, particularly in the development of advanced materials with specific properties. Overall, this chemical has diverse applications and continues to be of interest in various scientific fields.

InChI:InChI=1/C22H20O4/c1-24-21-14-19(22(23)26-16-18-10-6-3-7-11-18)12-13-20(21)25-15-17-8-4-2-5-9-17/h2-14H,15-16H2,1H3

Upstream product

• 121-34-6 3-methoxy-4-hydroxybenzoic acid 
• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 

Downstream Products

• 27883-60-9 4-hydroxy-5-methoxy-2-nitrobenzoic acid methyl ester 
• 61032-41-5 methyl 4-(benzyloxy)-5-methoxy-2-nitrobenzoate 
• 260546-06-3 (11aS)-8-benzyloxy-7-methoxy-2-methylidene-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one 
• 1253587-29-9 (6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)methyl 3-methoxy-4-hydroxybenzoate 
• 1253587-35-7 (6-benzyloxy-2,5,7,8-tetramethylchroman-2-yl)methyl 3-methoxy-4-benzyloxybenzoate 
• 1486-52-8 3-methoxy-4-benzyloxybenzoyl chloride 

Relevant articles and documents

VISUAL DETECTION OF PBD INDUCED DNA CROSSLINKS

The present invention relates to the field of oncology, laboratory tools and methods, and especially anti-tumor DNA crosslinking agents. Most patients with advanced solid tumors develop resistance to chemotherapy due to the ability of cancer cells to repair or tolerate sustained DNA damages. The inventors showed that the compounds according to the present invention allow the detection and visualization of alkylated DNA damages induced by PBDs without altering their DNA crosslinking ability. This enables the study of the effect and properties of PBDs. In particular, the present invention relates new derivates of PBD molecules and their synthesis. The present invention also relates to a method for visualizing DNA crosslinking; to a method for assessing the resistance of a tumor to a crosslinking agent and to a method for identifying a molecule or treatment for improving the efficiency of a crosslinking agent.

NOVEL GLYCOSYLTRANSFERASE, NOVEL GLYCOSYLTRANSFERASE GENE, AND NOVEL GLYCOSYL DONOR COMPOUND

An object of the present invention is to provide a sugar donating reagent comprising a sugar donor compound other than a sugar nucleotide and an enzyme capable of catalyzing a glycosyl transfer reaction using a sugar donor compound other than a sugar nucleotide. The present invention provides the following: a sugar donating reagent containing a compound of formula (A): wherein R 1 is independently selected from hydrogen, or C 1-6 alkyl, C 2-6 alkenyl, and C 2-6 alkynyl in which each of the groups is unsubstituted or substituted with one or more groups selected from OH, F, Cl, Br, I, CN, NO 2 , and SO 2 , n is 0, 1, 2, 3, 4 or 5, m is 0 or 1, and X represents a monosaccharide bound via a 2 bond on its anomeric carbon; a glycosyltransferase capable of catalyzing a glycosyl transfer reaction using the sugar donor; and a glycosyltransferase gene comprising DNA encoding the glycosyltransferase.

Synthesis, radical scavenging activity, protection during storage, and frying by novel antioxidants

Novel antioxidants, derivatives of trolox, and selected phenolic acids have been prepared in good yields and fully characterized by 1H NMR, 13C NMR, and MS. Their antioxidant activities have been assessed by DPPH and ORAC assays, and during frying and accelerated storage tests. Novel phenolic compounds exhibited higher radical scavenging activities than both trolox and R-tocopherol. Trolox hydroxybenzoate showed a significantly higher protection than R-tocopherol under storage conditions. All new antioxidants performed better than R-tocopherol under frying conditions. Moreover, their outstanding thermal stability makes them more valuable than R-tocopherol for frying applications.