912265-92-0

Basic information

• Product Name: 3a,6,7,7a-Tetrahydro-4H-isoxazolo[4,5-c]pyridine-3,5-dicarboxylic acid 5-tert-butyl ester 3-ethyl ester
• Synonyms: 3a,6,7,7a-Tetrahydro-4H-isoxazolo[4,5-c]pyridine-3,5-dicarboxylic acid 5-tert-butyl ester 3-ethyl ester;5-TERT-BUTYL 3-ETHYL 4H,5H,6H,7H-[1,2]OXAZOLO[4,5-C]PYRIDINE-3,5-DICARBOXYLATE(WXC06276);5-TERT-BUTYL 3-ETHYL 4H,5H,6H,7H-[1,2]OXAZOLO[4,5-C]PYRIDINE-3,5-DICARBOXYLATE
• CAS NO: 912265-92-0
• Molecular Formula: C14H22N2O5
• Molecular Weight: 298.33488
• Mol File: 912265-92-0.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3a,6,7,7a-Tetrahydro-4H-isoxazolo[4,5-c]pyridine-3,5-dicarboxylic acid 5-tert-butyl ester 3-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3a,6,7,7a-Tetrahydro-4H-isoxazolo[4,5-c]pyridine-3,5-dicarboxylic acid 5-tert-butyl ester 3-ethyl ester(912265-92-0)
• EPA Substance Registry System: 3a,6,7,7a-Tetrahydro-4H-isoxazolo[4,5-c]pyridine-3,5-dicarboxylic acid 5-tert-butyl ester 3-ethyl ester(912265-92-0)

Safety Data

• Hazardous Substances Data: 912265-92-0(Hazardous Substances Data)

Upstream product

• 207691-65-4 N-tert-butoxycarbonyl-4-(tetrahydropyrrole-1-yl)-1,2,3,6-tetrahydropyridine 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 1190971-34-6 5-tert-butyl 3-ethyl 7a-(pyrrolidin-1-yl)-3a,4,7,7a-tetrahydroisoxazolo[4,5-c]pyridine-3,5(6H)-dicarboxylate 
• 104916-29-2 1-Acetyl-4-(1-pyrrolidinyl)-1,2,3,6-tetrahydro-pyridine 
• 912265-89-5 5-acetyl-7a-pyrrolidin-1-yl-3a,4,5,6,7,7a-hexahydro-isoxazolo[4,5-c]pyridine-3-carboxylic acid-ethyl ester 
• 912265-90-8 5-acetyl-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyridine-3-carboxylic acid-ethyl ester 
• 32161-06-1 1-acetyl-4-piperidinone 
• 912330-17-7 ethyl 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine-3-carboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 912265-91-9 4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyridine-3-carboxylic acid-ethyl ester hydrochloride 

Downstream Products

• 912265-91-9 4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyridine-3-carboxylic acid-ethyl ester hydrochloride 
• 1190969-82-4 3-(1-(4-chloro-2,5-dimethylphenylsulfonyl)piperidin-2-yl)-1-(3-(piperidine-1-carbonyl)-6,7-dihydroisoxazolo[4,5-c]pyridin-5(4H)-yl)propan-1-one 
• 912265-93-1 5-[(tert-butoxy)carbonyl]-4H,5H,6H,7H-[1,2]oxazolo[4,5-c]pyridine-3-carboxylic acid 

Relevant articles and documents

BICYCLIC JAK INHIBITORS AND USES THEREOF

Provided herein are compounds of Formulas (I), (II), (III), and (IV) and subformulas thereof, wherein the variables are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I), (II), (III), or (IV) and methods of using the compounds, e.g., in the treatment of immune disorders, inflammatory disorders, and cancer.

SUBSTITUTED 4,5,6,7-TETRAHYDRO-ISOXAZOLO[4,5-C]PYRIDINE COMPOUNDS AND THEIR USE IN THE PRODUCTION OF MEDICAMENTS

The invention relates to substituted 4, 5, 6, 7-tetrahydro-isoxazolo [4, 5-c] pyridine compounds of formula (I), to a method for their production, to medicaments containing said compounds and to the use of said compounds for producing medicaments. It has been found that substituted 4,5,6,7-tetrahydro-isoxazolo[4,5-c] pyridine compounds of general formula (I) are suitable for noradrenaline receptor regulation, in particular for inhibiting the noradrenaline (NA) uptake, for 5-HT receptor regulation, in particular for inhibiting the 5-hydroxy-tryptophan (5-HT) uptake and/or for batrachotoxin (BTX) receptor regulation and can thus be used in particular as pharmaceutical active ingredients in medicaments for the prophylaxis and/or treatment of disorders or diseased that are associated with said receptors or processes.