912265-93-1

Basic information

• Product Name: 3a,6,7,7a-Tetrahydro-4H-isoxazolo[4,5-c]pyridine-3,5-dicarboxylic acid 5-tert-butyl ester
• Synonyms: 3a,6,7,7a-Tetrahydro-4H-isoxazolo[4,5-c]pyridine-3,5-dicarboxylic acid 5-tert-butyl ester;5-[(Tert-Butoxy)Carbonyl]-4H,5H,6H,7H-[1,2]Oxazolo[4,5-C]Pyridine-3-Carboxylic Acid;5-(tert-butoxycarbonyl)-4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine-3-carboxylic acid
• CAS NO: 912265-93-1
• Molecular Formula: C12H18N2O5
• Molecular Weight: 270.28172
• Mol File: 912265-93-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 452.3±45.0 °C(Predicted)
• Appearance: /
• Density: 1.321±0.06 g/cm3(Predicted)
• PKA: 3.27±0.20(Predicted)
• CAS DataBase Reference: 3a,6,7,7a-Tetrahydro-4H-isoxazolo[4,5-c]pyridine-3,5-dicarboxylic acid 5-tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3a,6,7,7a-Tetrahydro-4H-isoxazolo[4,5-c]pyridine-3,5-dicarboxylic acid 5-tert-butyl ester(912265-93-1)
• EPA Substance Registry System: 3a,6,7,7a-Tetrahydro-4H-isoxazolo[4,5-c]pyridine-3,5-dicarboxylic acid 5-tert-butyl ester(912265-93-1)

Safety Data

• Hazardous Substances Data: 912265-93-1(Hazardous Substances Data)

Usage

General Description

The chemical 3a,6,7,7a-Tetrahydro-4H-isoxazolo[4,5-c]pyridine-3,5-dicarboxylic acid 5-tert-butyl ester is a compound with potential pharmaceutical applications. It belongs to the class of isoxazolo compounds and is specifically an ester derivative of a dicarboxylic acid. This chemical is characterized by its tetrahydro-4H-isoxazolo[4,5-c]pyridine core structure, and the presence of a tert-butyl group attached to the carboxylic acid moiety. The compound's structure and functional groups make it a potential candidate for drug development, particularly in the field of neurological and psychiatric disorders. Further research and testing are necessary to fully understand and harness the potential pharmacological properties of this compound.

Upstream product

• 207691-65-4 N-tert-butoxycarbonyl-4-(tetrahydropyrrole-1-yl)-1,2,3,6-tetrahydropyridine 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 1190971-34-6 5-tert-butyl 3-ethyl 7a-(pyrrolidin-1-yl)-3a,4,7,7a-tetrahydroisoxazolo[4,5-c]pyridine-3,5(6H)-dicarboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 912330-17-7 ethyl 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine-3-carboxylate 
• 104916-29-2 1-Acetyl-4-(1-pyrrolidinyl)-1,2,3,6-tetrahydro-pyridine 
• 912265-91-9 4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyridine-3-carboxylic acid-ethyl ester hydrochloride 
• 912265-89-5 5-acetyl-7a-pyrrolidin-1-yl-3a,4,5,6,7,7a-hexahydro-isoxazolo[4,5-c]pyridine-3-carboxylic acid-ethyl ester 
• 912265-90-8 5-acetyl-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyridine-3-carboxylic acid-ethyl ester 
• 32161-06-1 1-acetyl-4-piperidinone 
• 912265-92-0 6,7-dihydro-4H-isoxazolo[4,5-c]pyridine-3,5-dicarboxylic acid-3-ethyl ester-5-tert-butyl ester 

Relevant articles and documents

BICYCLIC JAK INHIBITORS AND USES THEREOF

Provided herein are compounds of Formulas (I), (II), (III), and (IV) and subformulas thereof, wherein the variables are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I), (II), (III), or (IV) and methods of using the compounds, e.g., in the treatment of immune disorders, inflammatory disorders, and cancer.

SUBSTITUTED 4,5,6,7-TETRAHYDRO-ISOXAZOLO[4,5-C]PYRIDINE COMPOUNDS AND THEIR USE IN THE PRODUCTION OF MEDICAMENTS

The invention relates to substituted 4, 5, 6, 7-tetrahydro-isoxazolo [4, 5-c] pyridine compounds of formula (I), to a method for their production, to medicaments containing said compounds and to the use of said compounds for producing medicaments. It has been found that substituted 4,5,6,7-tetrahydro-isoxazolo[4,5-c] pyridine compounds of general formula (I) are suitable for noradrenaline receptor regulation, in particular for inhibiting the noradrenaline (NA) uptake, for 5-HT receptor regulation, in particular for inhibiting the 5-hydroxy-tryptophan (5-HT) uptake and/or for batrachotoxin (BTX) receptor regulation and can thus be used in particular as pharmaceutical active ingredients in medicaments for the prophylaxis and/or treatment of disorders or diseased that are associated with said receptors or processes.