912277-45-3

Basic information

• Product Name: 5H-Cyclopenta[b]pyridin-7-ol, 6,7-dihydro,(7R)-
• Synonyms: 5H-Cyclopenta[b]pyridin-7-ol, 6,7-dihydro,(7R)-;(R)-6,7-dihydro-5H-cyclopenta[b]pyridin-7-ol
• CAS NO: 912277-45-3
• Molecular Formula: C₈H₉NO
• Molecular Weight: 135.16316
• Mol File: 912277-45-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 291.2±25.0 °C(Predicted)
• Appearance: /
• Density: 1.243±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 13.30±0.20(Predicted)
• CAS DataBase Reference: 5H-Cyclopenta[b]pyridin-7-ol, 6,7-dihydro,(7R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 5H-Cyclopenta[b]pyridin-7-ol, 6,7-dihydro,(7R)-(912277-45-3)
• EPA Substance Registry System: 5H-Cyclopenta[b]pyridin-7-ol, 6,7-dihydro,(7R)-(912277-45-3)

Safety Data

• Hazardous Substances Data: 912277-45-3(Hazardous Substances Data)

Upstream product

• 90685-58-8 6,7-dihydro-5H-cyclopenta[b]pyridine 1-oxide 
• 533-37-9 2,3-cyclopentenopyridine 
• 31170-78-2 5H,6H,7H-cyclopenta[b]pyridin-7-one 
• 41598-71-4 7-hydroxy-6,7-dihydro-5H-cyclopenta[b]pyridine 
• 108-05-4 vinyl acetate 
• 90685-59-9 6,7-dihydro-5H-cyclopenta[b]pyridin-7-yl acetate 

Downstream Products

• 912277-28-2 (R)-6,7-dihydro-5H-[1]pyrindin-7-yl dicyclohexylphosphinite 
• 912277-17-9 (R)-6,7-dihydro-5H-[1]pyrindin-7-yl diphenylphosphinite 

Relevant articles and documents

COMPOUNDS AND METHODS FOR INHIBITING HISTONE DEMETHYLASES

The present application relates to compounds being of Formula (I), (II), (III), (IV), (V), (VI), (Ilia), (Illb), (IIIc), (Hid), (Hie), (Illf), and (Illg). Compounds of Formula (I) have the structure: wherein Q, R1, R18, R19, M, A and Y are as defined herein. The compounds of the application can modulate the activity of histone demethylases (HDMEs), and can be useful for the prevention and/or treatment of diseases in which genomic dysregulation is involved in the pathogenesis, e.g., cancer.

Iridium catalysts with bicyclic pyridine-phosphinite ligands: Asymmetric hydrogenation of olefins and furan derivatives

(Chemical Equation Presented) Superior bicyclics: Iridium catalysts as 1 derived from pyridine-phosphinite ligands considerably extend the scope of asymmetric hydrogenation. In addition to various unfunctionalized and functionalized olefins, furans, and benzofurans, for which no catalysts were known before, are also hydrogenated with high enantioselectivity (see scheme).