912480-83-2

Basic information

• Product Name: (R,E)-dimethyl(phenyl)(1-phenyl-1-penten-3-yl)silane
• Synonyms: (R,E)-dimethyl(phenyl)(1-phenyl-1-penten-3-yl)silane
• CAS NO: 912480-83-2
• Molecular Weight: 280.485
• Mol File: 912480-83-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R,E)-dimethyl(phenyl)(1-phenyl-1-penten-3-yl)silane(CAS DataBase Reference)
• NIST Chemistry Reference: (R,E)-dimethyl(phenyl)(1-phenyl-1-penten-3-yl)silane(912480-83-2)
• EPA Substance Registry System: (R,E)-dimethyl(phenyl)(1-phenyl-1-penten-3-yl)silane(912480-83-2)

Safety Data

• Hazardous Substances Data: 912480-83-2(Hazardous Substances Data)

Upstream product

• 104-55-2 3-phenyl-propenal 
• 1234935-78-4 (dimethyl(phenyl)silyl)zinc chloride 
• 103729-97-1 (S)-trans-1-phenylpent-1-en-3-ol 
• 91076-08-3 bis(dimethylphenylsilyl)zinc 
• 135758-87-1 (1S,2E)-benzoic acid 1-methyl-3-phenylallyl ester 
• 148614-78-2 (E)-1-phenyl-1-penten-3-yl phenyl carbamate 

Relevant articles and documents

Synthesis of Allylsilanes via Nickel-Catalyzed Cross-Coupling of Silicon Nucleophiles with Allyl Alcohols

NiCl2(PMe3)2-catalyzed reaction of allyl alcohols with silylzinc reagents, including PhMe2SiZnCl, Ph2MeSiZnCl, and Ph3SiZnCl, was performed, achieving allylsilanes in high yields. Aryl- and heteroaryl-substituted allyl alcohols, (E)-3-arylprop-2-en-1-ols, 1-aryl-prop-2-en-1-ols, and (E)-1-phenylpent-1-en-3-ol can be employed in the transformation. A range of functional groups as well as heteroaryl groups were tolerated. Reaction exhibited high regioselectivity and E/Z-selectivity when 1- or 3-aryl-substituted allyl alcohols were used as the substrates. Reaction of chiral allyl alcohol, (S,E)-1-phenylpent-1-en-3-ol, yielded a configuration-inversion product (R,E)-dimethyl(phenyl)(1-phenylpent-1-en-3-yl)silane.