91250-61-2Relevant academic research and scientific papers
Efficient Pd-Catalyzed Dehydrogenative Coupling of P(O)H with RSH: A Precise Construction of P(O)-S Bonds
Zhu, Yueyue,Chen, Tieqiao,Li, Shan,Shimada, Shigeru,Han, Li-Biao
, p. 5825 - 5828 (2016)
A Pd-catalyzed dehydrogenative phosphorylation of thiols is developed. A variety of thiols dehydrogenatively couple readily with all three kinds of P(O)-H compounds, i.e., H-phosphonates, H-phosphinates, and secondary phosphine oxides, providing a general access to the valuable phosphorothioates including the P-chiral compounds. A plausible mechanism is proposed.
