913370-09-9

Basic information

• Product Name: 1,2-Propanediol, 3-cyclohexyl-3-phenyl-3-(phenylmethoxy)-, (2R,3S)-
• CAS NO: 913370-09-9
• Molecular Formula: C22H28O3
• Molecular Weight: 340.463
• Mol File: 913370-09-9.mol

Chemical Properties

• CAS DataBase Reference: 1,2-Propanediol, 3-cyclohexyl-3-phenyl-3-(phenylmethoxy)-, (2R,3S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Propanediol, 3-cyclohexyl-3-phenyl-3-(phenylmethoxy)-, (2R,3S)-(913370-09-9)
• EPA Substance Registry System: 1,2-Propanediol, 3-cyclohexyl-3-phenyl-3-(phenylmethoxy)-, (2R,3S)-(913370-09-9)

Safety Data

• Hazardous Substances Data: 913370-09-9(Hazardous Substances Data)

Upstream product

• 913370-07-7 (R)-2-((S)-Benzyloxy-cyclohexyl-phenyl-methyl)-1,4-dioxa-spiro[4.5]decane 
• 913370-05-5 (2R)-1,2-O-cyclohexylidene-3-phenylpropane-3-ol 
• 654077-26-6 (2R)-1,2-O-cyclohexylidene-3-phenylpropan-3-one 
• 913370-06-6 (2R,1S)-1-cyclohexyl-1-phenyl-2,3-cyclohexylideneglycerol 

Downstream Products

• 20585-32-4 (S)-(+)-2-cyclohexyl-2-hydroxy-2-phenylacetaldehyde 
• 20585-34-6 (S)-cyclohexylmandelic acid 
• 913370-10-2 (S)-Benzyloxy-cyclohexyl-phenyl-acetaldehyde 

Relevant articles and documents

An efficient asymmetric synthesis of (S)-2-cyclohexyl-2-phenylglycolic acid, the acid segment of oxybutynin

An innovative and facile synthesis of the title compound has been developed starting from (R)-cyclohexylidene glyceraldehyde. The key step in the synthesis is a chiral template-driven Grignard addition with absolute diastereocontrol. The other attractive features are the operational simplicity and the use of inexpensive compounds/reagents.