913370-07-7

Upstream product

• 913370-06-6 (2R,1S)-1-cyclohexyl-1-phenyl-2,3-cyclohexylideneglycerol 
• 100-39-0 benzyl bromide 
• 78008-36-3 (R)-2,3-cyclohexylideneglyceraldehyde 
• 654077-26-6 (2R)-1,2-O-cyclohexylidene-3-phenylpropan-3-one 
• 913370-05-5 (2R)-1,2-O-cyclohexylidene-3-phenylpropane-3-ol 

Downstream Products

• 20585-32-4 (S)-(+)-2-cyclohexyl-2-hydroxy-2-phenylacetaldehyde 
• 20585-34-6 (S)-cyclohexylmandelic acid 
• 913370-10-2 (S)-Benzyloxy-cyclohexyl-phenyl-acetaldehyde 
• 913370-09-9 (2R,3S)-3-Benzyloxy-3-cyclohexyl-3-phenyl-propane-1,2-diol 

Relevant academic research and scientific papers

An efficient asymmetric synthesis of (S)-2-cyclohexyl-2-phenylglycolic acid, the acid segment of oxybutynin

An innovative and facile synthesis of the title compound has been developed starting from (R)-cyclohexylidene glyceraldehyde. The key step in the synthesis is a chiral template-driven Grignard addition with absolute diastereocontrol. The other attractive features are the operational simplicity and the use of inexpensive compounds/reagents.