913370-05-5

Basic information

• Product Name: (2R)-1,2-O-cyclohexylidene-3-phenylpropane-3-ol
• Synonyms: (2R)-1,2-O-cyclohexylidene-3-phenylpropane-3-ol
• CAS NO: 913370-05-5
• Molecular Weight: 248.322
• Mol File: 913370-05-5.mol

Chemical Properties

• CAS DataBase Reference: (2R)-1,2-O-cyclohexylidene-3-phenylpropane-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-1,2-O-cyclohexylidene-3-phenylpropane-3-ol(913370-05-5)
• EPA Substance Registry System: (2R)-1,2-O-cyclohexylidene-3-phenylpropane-3-ol(913370-05-5)

Safety Data

• Hazardous Substances Data: 913370-05-5(Hazardous Substances Data)

Upstream product

• 78008-36-3 (R)-2,3-cyclohexylideneglyceraldehyde 
• 108-86-1 bromobenzene 

Downstream Products

• 20585-32-4 (S)-(+)-2-cyclohexyl-2-hydroxy-2-phenylacetaldehyde 
• 20585-34-6 (S)-cyclohexylmandelic acid 
• 913370-07-7 (R)-2-((S)-Benzyloxy-cyclohexyl-phenyl-methyl)-1,4-dioxa-spiro[4.5]decane 
• 913370-06-6 (2R,1S)-1-cyclohexyl-1-phenyl-2,3-cyclohexylideneglycerol 
• 913370-09-9 (2R,3S)-3-Benzyloxy-3-cyclohexyl-3-phenyl-propane-1,2-diol 
• 913370-08-8 (2R,1S)-1-cyclohexyl-1-phenylglycerol 
• 913370-10-2 (S)-Benzyloxy-cyclohexyl-phenyl-acetaldehyde 
• 654077-26-6 (2R)-1,2-O-cyclohexylidene-3-phenylpropan-3-one 

Relevant articles and documents

An efficient asymmetric synthesis of (S)-2-cyclohexyl-2-phenylglycolic acid, the acid segment of oxybutynin

An innovative and facile synthesis of the title compound has been developed starting from (R)-cyclohexylidene glyceraldehyde. The key step in the synthesis is a chiral template-driven Grignard addition with absolute diastereocontrol. The other attractive features are the operational simplicity and the use of inexpensive compounds/reagents.

Diastereoselective Synthesis of syn-Alkanetriols from a Glyceral Derivative via K-Selectride Reduction: Application to the Synthesis of a Pheromone of the Sugarcane Weevils

K-selectride reduction of commercially available D-mannitol derived ketones 2b-i produced the corresponding alcohols 3b-i in good yields and with absolute syn-selectivity in almost all the cases. It was proposed that the bulky cyclohexylidene moiety of 3