91348-67-3

Basic information

• Product Name: N-(5-bromopyrimidin-2-yl)-4-methylbenzenesulfonamide
• Synonyms: N-(5-bromopyrimidin-2-yl)-4-methylbenzenesulfonamide
• CAS NO: 91348-67-3
• Molecular Weight: 328.189
• Mol File: 91348-67-3.mol

Chemical Properties

• CAS DataBase Reference: N-(5-bromopyrimidin-2-yl)-4-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-bromopyrimidin-2-yl)-4-methylbenzenesulfonamide(91348-67-3)
• EPA Substance Registry System: N-(5-bromopyrimidin-2-yl)-4-methylbenzenesulfonamide(91348-67-3)

Safety Data

• Hazardous Substances Data: 91348-67-3(Hazardous Substances Data)

Upstream product

• 7752-82-1 5-bromo-2-aminopyrimidine 
• 98-59-9 p-toluenesulfonyl chloride 
• 16699-14-2 4-methyl-N-(pyrimidin-2-yl)benzenesulfonamide 
• 7726-95-6 bromine 
• 108-24-7 acetic anhydride 
• 64-19-7 acetic acid 

Downstream Products

• 257290-77-0 2-(5-bromo-2-(tosylimino)pyrimidin-1(2H)-yl)acetamide 

Relevant articles and documents

Discovery of a novel 2,3-dimethylimidazo[1,2-a]pyrazine-6-carboxamide M4 positive allosteric modulator (PAM) chemotype

This Letter details our efforts to discover structurally unique M4 PAMs containing 5,6-heteroaryl ring systems. In an attempt to improve the DMPK profiles of the 2,3-dimethyl-2H-indazole-5-carboxamide and 1-methyl-1H-benzo[d][1,2,3]triazole-6-carboxamide cores, we investigated a plethora of core replacements. This exercise identified a novel 2,3-dimethylimidazo[1,2-a]pyrazine-6-carboxamide core that provided improved M4 PAM activity and CNS penetration.

IMIDAZOPYRIDINE DERIVATIVES AND AZA-IMIDAZOPYRIDINE DERIVATIVES AS JANUS KINASE 2 INHIBITORS AND USES THEREOF

The present disclosure provides compounds of Formula (I′) (e.g., compounds of Formula (I)), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, cocrystals, tautomers, stereoisomers, isotopically labeled derivatives, and prodrugs thereof

HARMFUL ARTHROPOD CONTROL METHOD USING HETEROCYCLIC COMPOUND

PROBLEM TO BE SOLVED: To provide a method for controlling a harmful arthropod. SOLUTION: The compound shown by the formula (I) [in the formula, Q represents the group, etc. represented by the formula Q1, Z represents an oxygen atom, etc., A1 re

Unusual ring closure reaction of amides with pyrimidines: Novel stereoselective synthesis of hexahydroimidazo[1,2-c]pyrimidines

Hexahydromidazo[1,2-c]pyrimidines 6 were prepared by the reaction of tosylpyrimidines 2 with bromoacetamides 3 in one step. The stereoselectivity of the reaction has been confirmed by X-ray analysis. Imidazo[1,2- a]pyrimidines 5 were obtained on heating h