91352-76-0Relevant articles and documents
Ru(II)-functionalized SBA-15 as highly chemoselective, acid free and sustainable heterogeneous catalyst for acetalization of aldehydes and ketones
Lazar, Anish,Betsy,Vinod,Singh
, p. 62 - 66 (2017/10/31)
Combining electron deficient Ru(II) coordination sites with organofunctionalized SBA-15, (L)Ru(II)@SBA-15, result in a mild, neutral, water scavenger free and chemo-selective acetalization catalyst for cyclic/acyclic acetals. Vacant coordination sites of ruthenium in (L)Ru(II)@SBA-15 activates protecting groups as well as reactants simultaneously and restricts the reverse acetalization reaction. Synthesized (L)Ru(II)@SBA-15 catalyst has been thoroughly characterized and act as competitive catalyst compared to conventional acid catalysts. (L)Ru(II)@SBA-15 performs high catalytic activity as well as selectivity within 20 min with high TOF. The catalyst can be recycled and reaction parameters are optimized.
TAXANE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF
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Page 4; 14-16, (2008/06/13)
The invention discloses an oxazolidine intermediate for the synthesis of 14- beta -hydroxy-1,14-carbonate-baccatines bearing a 13-isoserine substituent, and a process for the preparation thereof.
Docetaxel (Taxotere) derivatives: novel NbCl3-based stereoselective approach to 2'-methyldocetaxel
Denis, Jean-Noeel,Fkyerat, Abdellatif,Gimbert, Yves,Coutterez, Claire,Mantellier, Pierre,et al.
, p. 1811 - 1816 (2007/10/02)
The C-2 methylated 2S,3R and 2R,3S side chains of docetaxel have been enantioselectively prepared and esterified with protected 10-deacetylbaccatin III to provide novel analogues of docetaxel.
FORMATION OF 2,2-Spiro-SUBSTITUTED 2,3-DIHYDROBENZOFURANS.
Morrison, George A.,Sammes, Peter G.,Simmonds, James P.
, p. 1037 - 1050 (2007/10/02)
Routes from substituted resorcinols to spiro-substituted dihydrobenzofurans are described.Whilst use of acid-catalysed condensations between a resorcinol and an aldehyde only gave low yields of dihydrobenzofurans and lacked regiocontrol, use of a nucleophilic aromatic substitution approach was successful.