913615-95-9Relevant academic research and scientific papers
Isolation and synthesis of analgesic and anti-inflammatory compounds from Ochna squarrosa L.
Anuradha,Srinivas, Pullela V.,Ranga Rao,Manjulatha,Purohit, Muralidhar G.,Madhusudana Rao
, p. 6820 - 6826 (2006)
Two new furanoflavonoids (1, 2), one new chalcone dimer (3) along with six known compounds, chrysophanol, 5-O-methyl squarrosin, 5-methoxy furano[4″,5″,6,7]flavone, calodenone, lophirone A and lophirone H were isolated from the ethyl acetate-soluble fraction of methanol extract of root bark of Ochna squarrosa. Chrysophanol, calodenone, lophirone A and lophirone H were isolated from this plant for the first time. The structures of all the isolated compounds were confirmed by 1D and 2D spectroscopic data. These compounds were tested for analgesic and anti-inflammatory activity. All the new compounds showed good analgesic and anti-inflammatory activity. A simple and facile method for the cleavage of benzyl ethers using I2 in trigol is also reported.
Synthesis of antihyperglycemic, α-glucosidase inhibitory, and DPPH free radical scavenging furanochalcones
Rao, R. Ranga,Tiwari, Ashok K.,Reddy, P. Prabhakar,Babu, K. Suresh,Suresh,Ali, A. Zehra,Madhusudana,Agawane, Sachin B.,Badrinarayan, Preethi,Sastry, G. Narahari,Rao, J. Madhusudana
experimental part, p. 760 - 774 (2012/09/22)
A series of furanochalcone derivatives have been designed and synthesized. Molecular modeling studies were carried out to probe into the mechanism of binding of chalcone inhibitors and understand the structure-activity relationship to identify the contrib
