91397-03-4

Usage

InChI:InChI=1/C12H11N3OS/c1-9-11(13-8-17)12(16)15(14(9)2)10-6-4-3-5-7-10/h3-7H,1-2H3

Upstream product

• 83-07-8 4-amino-2,3-dimethyl-1-phenylpyrazolin-5-one 
• 67-66-3 chloroform 
• 75-15-0 carbon disulfide 
• 463-71-8 thiophosgene 

Downstream Products

• 73791-36-3 <5-Oxo-2,3-dimethyl-1-phenyl-Δ³-pyrazolinyl-(4)>-thiocarbamidsaeure-morpholid 
• 73953-59-0 N-(4-antipyrinyl)-N'-(2-pyridyl) thiourea 
• 26084-35-5 di-(2,3-dimethyl-1-phenyl-4-pyrazolon-5-yl)-thiourea 
• 898552-60-8 2-(4-chloro-phenyl)-5-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-4-thioxo-4,5-dihydro-1-oxa-3b,5-diaza-cyclopenta[a]pentalen-6-one 

Relevant academic research and scientific papers

ISOTHIOCYNATES AND GLUCOSINOLATE COMPOUNDS AND ANTI-TUMOR COMPOSITIONS CONTAINING SAME

The present invention provides glucosinolate and isothiocyanate compounds and related methods for synthesizing these compounds and analogs. In certain embodiments, these glucosinolate and isothiocyanate compounds are useful and chemopreventive and or chemotherapeutic agents.

ISOTHIOCYANATES AND GLUCOSINOLATE COMPOUNDS AND ANTI-TUMOR COMPOSITIOS CONTAINING SAME

The present invention provides glucosinolate and isothiocyante compounds and related methods for synthesizing these compounds and analogs. In certain embodiments, these glucosinolate and isothiocyanate compounds are useful and chemopreventive and or chemotherapeutic agents.

Rigidified Compounds for Modulating Heparanase Activity

Disclosed are novel rigidified compounds having a rhodanine-like residue and at least one aryl or heteroaryl residue linked to the rhodanine-like residue, whereby a core structure of these compounds, as defined in the specification, is characterized as having one or zero free-to-rotate bonds. Also disclosed are pharmaceutical compositions containing these rigidified compounds and uses thereof for modulating the activity of heparanase and hence in the treatment of heparanase-associated diseases and disorders, and uses thereof for modulating the activity of heparin-binding proteins and hence in the treatment of heparin-binding proteins-associated diseases and disorders as well as in the treatment of medical conditions that are at least partially treatable by rhodanine or a rhodanine analog.

A microwave-assisted solid-state synthesis and characterization of diheterocyclic thioureas

In this study, a number of new diheterocyclic thioureas have been synthesized under microwave irradiation coupled with solvent-free condition, which proves to be simple and efficient. The structures of the prepared compounds are characterized by elemental

Synthesis and characterization of a new series of 3-(4-antipyrinyl)-2-thiohydantoin derivatives

This paper reports the reaction of 4-antipyrinyl isothiocyanate with DL-amino acids affording a new heterocyclic series of 3-(4-antipyrinyl)-2-thiohydantoin derivatives in mild conditions. The reaction proves to be simple and the experiment is easy to ope