914095-13-9

Basic information

• Product Name: (4,5-Difluoro-2-nitro-phenyl)-Methanol
• Synonyms: (4,5-Difluoro-2-nitro-phenyl)-Methanol
• CAS NO: 914095-13-9
• Molecular Formula: C₇H₅F₂NO₃
• Molecular Weight: 189.1163064
• Mol File: 914095-13-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (4,5-Difluoro-2-nitro-phenyl)-Methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (4,5-Difluoro-2-nitro-phenyl)-Methanol(914095-13-9)
• EPA Substance Registry System: (4,5-Difluoro-2-nitro-phenyl)-Methanol(914095-13-9)

Safety Data

• Hazardous Substances Data: 914095-13-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(4,5-Difluoro-2-nitro-phenyl)-Methanol is used as a building block for the development of new drugs due to its unique structure and potential biological activities.
Used in Agrochemical Industry:
(4,5-Difluoro-2-nitro-phenyl)-Methanol is used as a building block for the development of new pesticides due to its unique structure and potential biological activities.

Upstream product

• 20372-63-8 4,5-difluoro-2-nitrobenzoic acid 

Downstream Products

• 149169-49-3 4,5-difluoro-2-nitrobenzaldehyde 
• 1175668-36-6 [5-(3-[1,3]dioxan-2-yl-phenylsulfanyl)-4-fluoro-2-nitro-phenyl]-methanol 
• 946430-93-9 (4-Fluoro-2-nitro-5-phenoxy-phenyl)-methanol 

Relevant articles and documents

1H-PYRROLE-2,5-DIONE COMPOUNDS AND METHODS OF USING THEM TO INDUCE SELF-RENEWAL OF STEM/PROGENITOR SUPPORTING CELLS

The present invention relates to 1H-pyrrole-2,5-dione compounds and methods of using them to induce self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into tissue cells.

FUSED QUADRACYCLIC COMPOUNDS, COMPOSITIONS AND USES THEREOF

Provided herein are substituted fused quadracyclic compounds useful as inhibitors of MK2. The invention further provides pharmaceutical compositions of the compounds of the invention. The invention also provides medical uses of substituted fused quadracyclic compounds.

6-SUBSTITUTED-THIO-2-AMINO-QUINOLINE DERIVATIVES USEFUL AS INHIBITORS OF β-SECRETASE (BACE)

The present invention is directed to 6-substituted-thio-2-amino-quinoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD), mild cognitive impairment, senility and / or dementia. The compounds of the present invention are inhibitors of β- secretase, also known as β-site amyloid cleaving enzyme, BACE, BACE1, Asp2, or memapsin2.

2-AMINO-QUINOLINE DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE (BACE)

The present invention is directed to 2-amino-quinoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of β-secretase, also known as β-site cleaving enzyme and BACE, BACE1, Asp2 and memapsin2.

4-PHENYL-5-OXO-1,4,5,6,7,8-HEXAHYDROQUINOLINE DERIVATIVES THE TREATMENT OF INFERTILITY

The present invention relates to 4-phenyl-5-oxo-l,4)5,6,7,8-hexahydroquinoline derivatives according to Formula I, Formula I or a pharmaceutically acceptable salt thereof, wherein R1 is (l-6C)alkyl, (2-6C)alkenyl or (2-6C)aDcynyl; R2, R3 are independently halogen, (l-4C)allcyl, (2-4C)alkenyl, (2-4C)- alkynyl, (1 -4C)aBcoxy, (3-4C)alkenyloxy or (3-4C)alkynyloxy; R4 is phenyl or (2-5C)- heteroaryl, both substituted with R7 and optionally substituted on the (hetero)aromatic ring with one or more substituents selected from hydroxy, amino, halogen, nitro, trifluoromethyl, cyano, (l-4C)alkyl, (l-4C)alkoxy , (l-4C)alkylthio and (di)(l-4C)- alkylamino. The invention also relates to pharmaceutical compositions comprising said derivatives, as well as to the use of these 4-phenyl-5-oxo-l, 4,5,6, 7,8-hexahydro- quinoline derivatives in therapy, more specifically for the treatment of infertility