914256-16-9Relevant academic research and scientific papers
Synthesis of new dihydropyrazoles of designed curcumin analogues
Tripathi, Vishwa Deepak
, p. 1889 - 1894 (2019/08/08)
Present work demonstrates a facile synthesis of a series of 20 dihydropyrazole derivatives from well designed curcumin analogues by reaction of chalcone derivatives with phenylhydrazine. All the synthesized compounds were characterized by spectroscopic (1H and 13C NMR, IR spectra), spectrometric (Mass spectra) data and elemental analysis. Synthesized dihydropyrazoles have diversity points on attached phenyl ring. Effect of substituent on reactivity was explained on the basis of electronic effect generated due to groups on phenyl ring. Presence of dd (double doublet) in 1H NMR spectrum of dihydropyrazoles was also explained due to presence of optically active carbon of pyrazole ring.
Iodine (III) mediated synthesis of new 5-aryl-3-(4-hydroxy-6-methyl-2H- pyran-2-oxo-3-yl)-1-phenylpyrazoles from dehydrogenation of 5-aryl-3-(4-hydroxy- 6-methyl-2H-pyran-2-oxo-3-yl)-1-phenylpyrazolines
Prakash, Om,Kumar, Ajay,Kinger, Mayank,Singh, Shiv P.
, p. 456 - 460 (2007/10/03)
3-Cinnamoyl-4-hydroxy-6-methyl-2-pyrones (chalcone analogs of DHA) on condensation with phenylhydrazine in ethanol, yield 5-aryl-3-(4-hydroxy-6- methyl-2H-pyran-2-oxo-3-yl)-1-phenylpyrazolines which undergo smooth dehydrogenation to the corresponding pyra
