914301-48-7Relevant articles and documents
Design, synthesis, and incorporation of a β-turn mimetic in angiotensin II forming novel pseudopeptides with affinity for AT1 and AT2 receptors
Rosenstr?m, Ulrika,Sk?ld, Christian,Lindeberg, Gunnar,Botros, Milad,Nyberg, Fred,Karlén, Anders,Hallberg, Anders
, p. 6133 - 6137 (2007/10/03)
A benzodiazepine-based β-turn mimetic has been designed, synthesized, and incorporated into angiotensin II. Comparison of the mimetic with β-turns in crystallized proteins showed that it most closely resembles a type II β-turn. The compounds exhibited hig