91437-85-3

Basic information

• Product Name: 1H-BENZIMIDAZOLE, 2-PHENYL-5-(TRIFLUOROMETHYL)-
• Synonyms: 1H-BENZIMIDAZOLE, 2-PHENYL-5-(TRIFLUOROMETHYL)-;2-Phenyl-6-(trifluoromethyl)-1H-benzo[d]imidazole
• CAS NO: 91437-85-3
• Molecular Formula: C₁₄H₉F₃N₂
• Molecular Weight: 262.23
• Mol File: 91437-85-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-BENZIMIDAZOLE, 2-PHENYL-5-(TRIFLUOROMETHYL)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-BENZIMIDAZOLE, 2-PHENYL-5-(TRIFLUOROMETHYL)-(91437-85-3)
• EPA Substance Registry System: 1H-BENZIMIDAZOLE, 2-PHENYL-5-(TRIFLUOROMETHYL)-(91437-85-3)

Safety Data

• Hazardous Substances Data: 91437-85-3(Hazardous Substances Data)

Upstream product

• 1224442-16-3 C₁₄H₁₀F₃N₃O₂ 
• 100-46-9 benzylamine 
• 368-71-8 4-(trifluoromethyl)-1,2-phenylenediamine 
• 1308866-07-0 N-benzyl-2-iodo-4-(trifluoromethyl)aniline 
• 100-39-0 benzyl bromide 
• 163444-17-5 2-iodo-4-(trifluoromethyl)aniline 

Relevant articles and documents

Copper-Catalyzed Double C-N Bond Formation for the Synthesis of Diverse Benzimidazoles from N -Alkyl-2-iodoaniline and Sodium Azide

An efficient approach to the synthesis of benzimidazole derivatives has been achieved by copper-catalyzed double C-N bonds formation of N-alkyl-2-iodoaniline and sodium azide. The reaction was supposed to proceed through copper-catalyzed tandem reaction of SNAr reaction, aerobic oxidation of C(sp3)-H bond and intramolecular C-N bond formation sequence. Structurally diverse 2-aryl, alkenyl and alkyl benzoimidazole derivatives were assembled by this methodology.

Catalyst/ligand-free synthesis of benzimidazoles and quinazolinones from amidines via intramolecular transamination reaction

An efficient catalyst/ligand-free synthesis of benzimidazoles and quinazolinones from amidines in quantitative yields has been described.