914389-37-0

Basic information

• Product Name: 2-(4-methoxyphenyl)-2,5-diazaspiro[3.4]octan-1-one
• Synonyms: 2-(4-Methoxyphenyl)-2,5-diazaspiro[3.4]octan-1-on
• CAS NO: 914389-37-0
• Molecular Formula: C₁₃H₁₆N₂O₂
• Molecular Weight: 232.28
• Mol File: 914389-37-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 486.8°C at 760 mmHg
• Flash Point: 248.2°C
• Density: 1.25g/cm³
• Vapor Pressure: 1.25E-09mmHg at 25°C
• Refractive Index: 1.613
• CAS DataBase Reference: 2-(4-methoxyphenyl)-2,5-diazaspiro[3.4]octan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methoxyphenyl)-2,5-diazaspiro[3.4]octan-1-one(914389-37-0)
• EPA Substance Registry System: 2-(4-methoxyphenyl)-2,5-diazaspiro[3.4]octan-1-one(914389-37-0)

Safety Data

• Hazardous Substances Data: 914389-37-0(Hazardous Substances Data)

Upstream product

• 1377324-41-8 tert-butyl 2-(4-methoxyphenyl)-1-oxo-2,5-diazaspiro[3.4]octane-5-carboxylate 
• 1621421-80-4 tert-butyl 2-(hydroxymethyl)-2-(4-methoxyphenylcarbamoyl)pyrrolidine-1-carboxylate 
• 1621421-78-0 1-tert-butyl 2-methyl 2-(4-methoxyphenylcarbamoyl)pyrrolidine-1,2-dicarboxylate 
• 1621421-76-8 1-(tert-butoxycarbonyl) 2-(methoxycarbonyl)pyrrolidine-2-carboxylic acid 
• 59936-29-7 (S)-N-(tert-butoxycarbonyl)proline methyl ester 
• 104-94-9 4-methoxy-aniline 
• 32752-37-7 1,3,5-tris(4-methoxyphenyl)-1,3,5-triazinane 
• 61350-60-5 (S)-benzyloxycarbonyl-proline acid chloride 
• 914389-32-5 (+/-)-5-benzyloxycarbonyl-2-(4-methoxyphenyl)-2,5-diazaspiro[3,4]octan-1-one 

Downstream Products

• 914389-51-8 (4R)-5-benzyloxycarbonyl-2-(tert-butoxycarbonyl)-2,5-diazaspiro[3,4]octan-1-one 
• 914389-50-7 (4R)-5-benzyloxycarbonyl-2-(4-methoxyphenyl)-2,5-diazaspiro[3,4]octan-1-one 
• 914389-52-9 2-(tert-butoxycarbonylamino-methyl)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester 
• 914389-53-0 2-(tert-butoxycarbonylamino-methyl)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 
• 914389-47-2 (S)-2-((R)-2-Carboxymethyl-1-oxo-2,5-diaza-spiro[3.4]octane-5-carbonyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 914389-44-9 (4R)-5-[(2S)-1-tert-butoxycarbonylpyrrolidin-2-ylcarbonyl]-2-(4-methoxyphenyl)-2,5-diazaspiro[3,4]octan-1-one 
• 914389-46-1 (4R)-2-[(benzyloxycarbonyl)methyl]-5-[(2S)-1-tert-butoxycarbonylpyrrolidin-2-ylcarbonyl]-2,5-diazaspiro[3,4]octan-1-one 
• 914389-48-3 (4R)-2-[3-aza-4-(benzyloxycarbonyl)-2-oxobutyl]-5-[(2S)-1-tert-butoxycarbonylpyrrolidin-2-ylcarbonyl]-2,5-diazaspiro[3,4]octan-1-one 
• 914389-54-1 (R)-2-({[(R)-1-Benzyloxycarbonyl-2-(tert-butoxycarbonylamino-methyl)-pyrrolidine-2-carbonyl]-amino}-methyl)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester 
• 914389-55-2 (R)-2-({[(R)-1-Benzyloxycarbonyl-2-({[(R)-1-benzyloxycarbonyl-2-(tert-butoxycarbonylamino-methyl)-pyrrolidine-2-carbonyl]-amino}-methyl)-pyrrolidine-2-carbonyl]-amino}-methyl)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester 
• 1621421-92-8 ethyl 2-methoxy-2-(2-(4-methoxyphenyl)-1-oxo-2,5-diazaspiro[3.4]octan-5-yl)acetate 
• 1621421-94-0 C₁₈H₂₄N₂O₅ 
• 1621421-96-2 C₁₆H₂₁N₃O₄ 
• 1621421-90-6 ethyl 2-(2-(4-methoxyphenyl)-1-oxo-2,5-diazaspiro[3.4]octan-5-yl)acetate 

Relevant articles and documents

SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF

Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related disorders. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.