32752-37-7

Usage

Chemical structure

Hexahydro-1,3,5-triazine with three 4-methoxyphenyl groups attached

Type of compound

Triazine derivative

Common uses

Synthesis of organic compounds, pharmaceuticals, building block in polymers and dyes

Potential applications

Medicine, agriculture, materials science

Industrial processes

Versatile ingredient in various processes and products due to its unique chemical structure and properties

Upstream product

• 50-00-0 formaldehyd 
• 104-94-9 4-methoxy-aniline 
• 1353053-97-0 triethylsiloxymethyl-N,N-dimethylamine 
• 229323-97-1 2,2-dihydroperoxyadamantane 
• 51-46-7 1,3,6,8-tetraazatricyclo[4.4.1.1^3,8]dodecane 
• 115163-00-3 2-anisidine 
• 78666-54-3 N,N'-bis-(4-methoxy-phenyl)-methanediamine 

Downstream Products

• 115957-20-5 1-(4-methoxyphenyl)-3-phthalimidoazetidin-2-one 
• 1026620-05-2 2-{tert-butoxy-[(4-methoxy-phenylamino)-methyl]-phosphinoylmethyl}-pentanedioic acid di-tert-butyl ester 
• 914389-32-5 (+/-)-5-benzyloxycarbonyl-2-(4-methoxyphenyl)-2,5-diazaspiro[3,4]octan-1-one 
• 933782-80-0 1-(4-methoxy-phenyl)-aziridine-2-carboxylic acid methyl ester 
• 914389-37-0 (+/-)-2-(4-methoxyphenyl)-2,5-diazaspiro[3,4]octan-1-one 
• 914389-40-5 (4R)-2-(4-methoxyphenyl)-2,5-diazaspiro[3,4]octan-1-one 
• 914389-38-1 (4S)-2-(4-methoxyphenyl)-2,5-diazaspiro[3,4]octan-1-one 
• 914389-50-7 (4R)-5-benzyloxycarbonyl-2-(4-methoxyphenyl)-2,5-diazaspiro[3,4]octan-1-one 
• 914389-44-9 (4R)-5-[(2S)-1-tert-butoxycarbonylpyrrolidin-2-ylcarbonyl]-2-(4-methoxyphenyl)-2,5-diazaspiro[3,4]octan-1-one 
• 3717-22-4 (Z)-para-methoxybenzaldehyde oxime 
• 3717-21-3 (E)-4-methoxybenzaldoxime 
• 1609104-84-8 4-acetyl-5-methyl-1-(4-methoxylphenyl)-1H-imidazole 
• 1609104-82-6 4-acetyl-1-(4-methoxyphenyl)-5-methyl-1,3-dihydro-2H-imidazol-2-one 

Relevant academic research and scientific papers

Ultrasound-assisted synthesis of substituted triazines and their corrosion inhibition behavior on N80 steel/acid interface

The three substituted triazines were synthesized by ultrasound irradiation method and characterized by FTIR, 13C NMR, and 1H NMR. The corrosion inhibition behavior of the synthesized inhibitors on N80 steel in 15% HCl was studied using electrochemical analyses and weight loss methods. All three inhibitors exhibited excellent corrosion inhibition performance, and the best inhibition effect was shown by TZ-3 (93.2% at 800 mg/L). EIS measurements suggest that the corrosion inhibition process is a charge transfer controlled. The PDP results indicated that all the triazines are mixed-type inhibitors. Langmuir adsorption model is the best fit among the other tested isotherms. These molecules can act as promising acidizing corrosion inhibitors for the oil gas industry. FTIR, AFM, and UV-vis studies corroborate the adsorption of inhibitor molecules over the metal surface.

Conformational Study of 1,3,5-Tris(o-methoxyphenyl)-1,3,5-triazacyclohexane and 1,3,5-Tris(p-methoxyphenyl)-1,3,5-triazacyclohexane

The triazacyclohexane ring in both title compounds, C24H27N3O3 (1a) and C24H27N3O3 (1b), adopts a chair conformation with an equatorial-diaxial orientation of the aryl groups.The repulsion between axial groups is relieved by the displacement of the N-C(ar

Role of the nucleophilicity of the amino group of benzidines in the synthesis of hemiaminal ethers

This paper presents a study of the reaction between some aromatic amines and formaldehyde in ethanol. Anisidines reacting with formaldehyde produced cyclic or linear aminals (hexahydrotriazines or methanediamines) whilst benzidines produced hemiaminal eth

Synthesis of Diversely Substituted Imidazolidines via [3+2] Cycloaddition of 1,3,5-Triazinanes with Donor-Acceptor Aziridines and Their Anti-Tumor Activity

A Y(OTf)3-catalyzed [3+2] cycloaddition of 1,3,5-triazinanes with donor-acceptor aziridines has been developed, accessing diversely substituted imidazolidines high efficiency. Mechanistic investigations support the formation of imidazolidines through an SN1-like pathway. Furthermore, these imidazolidines exhibit promising anti-tumor activity against a series of human cancer cell lines. (Figure presented.).

Divergent Synthesis of Aziridine and Imidazolidine Frameworks under Blue LED Irradiation

We develop a visible light-promoted divergent cycloaddition of α-diazo esters with hexahydro-1,3,5-triazines, leading to a series of aziridine and imidazolidine frameworks in average good yield, by simply changing the reaction media used. It is noteworthy that the reaction occurs under sole visible light irradiation without the need for exogenous photoredox catalysts. More significantly, a reasonable reaction mechanism was proposed on the basis of the control experiments and density functional theory calculation results.

Synthesis of α-Amino Tertiary Alkylperoxides by Lewis Acid-Catalyzed Peroxidation of 1,3,5-Triazines

α-Substituted peroxides have been found in natural products and are widely used as anti-malarial agents. Zn(OTf)2-catalyzed peroxidation of 1,3,5-triazines has been developed, accessing diversely substituted α-amino tertiary alkylperoxides with high efficiency. Mechanistic investigations and useful synthetic application of the products have also been presented.

Iridium-catalyzed 1,5-(aryl)aminomethylation of 1,3-enynes by alkenyl-to-allyl 1,4-iridium(i) migration

A novel multicomponent coupling reaction involving the iridium-catalyzed 1,5-difunctionalization of 1,3-enynes with arylboronic acids and triazinanes is described. A key step in this 1,5-(aryl)aminomethylation reaction is the alkenyl-to-allyl 1,4-iridium(i) migration.

Activation Relay on Rhodium-Catalyzed C-H Aminomethylation in Cooperation with Photoredox Catalysis

A site selective C-H aminomethylation at indole's C3 position has been achieved by merging rhodium(III)-catalyzed C-H activation and photoredox catalysis in a one-pot manner. An investigation of the mechanistic insights rationalized the essence of the activation relay and the combination mode.

Vinylethylene Carbonates as α,β-Unsaturated Aldehyde Surrogates for Regioselective [3 + 3] Cycloaddition

Herein, we report a novel stepwise addition-controlled ring size method, to access tetrahydropyrimidines through an operationally simple [3 + 3] cycloaddition of vinylethylene carbonates with triazinanes. Interestingly, we could also use this method for a [3 + 3] oxidative cycloaddition, which allows the facile synthesis of polysubstituted terphenyls under mild conditions. Mechanistic studies suggest that vinylethylene carbonates could generate α,β-unsaturated aldehydes as 3-carbon synthons for cycloaddition via a combination process of Pd-catalyzed decarboxylation and β-H elimination.

Preparation of spiro[imidazolidine-4,3′-indolin]-2′-imines: Via copper(i)-catalyzed formal [2 + 2 + 1] cycloaddition of 3-diazoindolin-2-imines and triazines

We report a facile and efficient synthesis of spiro[imidazolidine-4,3′-indolin]-2′-imines via a copper(i)-catalyzed cascade reaction of 3-diazoindolin-2-imines with 1,3,5-triazines. The reaction proceeds under very mild conditions and tolerates a variety of functional groups. The cascade process involves the formation of a copper-carbene intermediate and a formal [2 + 2 + 1] cycloaddition.