914458-21-2

Basic information

• Product Name: (1-Heptyl-5-phenyl-1H-pyrrol-3-yl)-1-naphthalenylMethanone
• Synonyms: (1-Heptyl-5-phenyl-1H-pyrrol-3-yl)-1-naphthalenylMethanone;JWH 146;(1-heptyl-5-phenylpyrrol-3-yl)-naphthalen-1-ylmethanone
• CAS NO: 914458-21-2
• Molecular Formula: C28H29NO
• Molecular Weight: 395.53596
• Product Categories: Aromatics, Heterocycles, Indole Derivatives, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 914458-21-2.mol

Chemical Properties

• Boiling Point: 575.1±38.0 °C(Predicted)
• Appearance: /
• Density: 1.05±0.1 g/cm3(Predicted)
• PKA: -6.47±0.70(Predicted)
• CAS DataBase Reference: (1-Heptyl-5-phenyl-1H-pyrrol-3-yl)-1-naphthalenylMethanone(CAS DataBase Reference)
• NIST Chemistry Reference: (1-Heptyl-5-phenyl-1H-pyrrol-3-yl)-1-naphthalenylMethanone(914458-21-2)
• EPA Substance Registry System: (1-Heptyl-5-phenyl-1H-pyrrol-3-yl)-1-naphthalenylMethanone(914458-21-2)

Safety Data

• Hazardous Substances Data: 914458-21-2(Hazardous Substances Data)

Usage

Uses

Used in Forensic Applications:
JWH 146 is used as a forensic tool for the detection and analysis of synthetic cannabinoids in various samples, such as herbal blends and other substances. Its high affinity for CB1 and CB2 receptors makes it a valuable compound for identifying and studying the presence of these substances in forensic investigations.
Used in Research Applications:
In research, JWH 146 serves as a valuable compound for studying the effects and mechanisms of action of synthetic cannabinoids on the central and peripheral cannabinoid receptors. This can help researchers better understand the potential therapeutic applications and risks associated with these compounds, as well as contribute to the development of new drugs and treatments.

Upstream product

• 914458-46-1 2-phenyl-4-(1-naphthoyl)-N-p-toluenesulfonylpyrrole 
• 613-91-2 acetophenone oxime 
• 153633-36-4 2-phenyl-1-(p-toluenesulfonyl)pyrrole 
• 3042-22-6 2-phenyl-1H-pyrrole 
• 914458-48-3 naphthalen-1-yl(5-phenyl-1H-pyrrol-3-yl)methanone 
• 629-04-9 1-Bromoheptane 

Relevant articles and documents

1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: New high affinity ligands for the cannabinoid CB1 and CB2 receptors

Two series of 1-alkyl-2-aryl-4-(1-naphthoyl)pyrroles were synthesized and their affinities for the cannabinoid CB1 and CB2 receptors were determined. In the 2-phenyl series (5) the N-alkyl group was varied from n-propyl to n-heptyl. A second series of 23 1-pentyl-2-aryl-4-(1-naphthoyl)-pyrroles (6) was also prepared. Several compounds in both series have CB1 receptor affinities in the 6-30 nM range. The high affinities of these pyrrole derivatives relative to JWH-030 (1, R = C5H11) support the hypothesis that these pyrroles interact with the CB1 receptor primarily by aromatic stacking.