914458-46-1

Basic information

• Product Name: 2-phenyl-4-(1-naphthoyl)-N-p-toluenesulfonylpyrrole
• Synonyms: 2-phenyl-4-(1-naphthoyl)-N-p-toluenesulfonylpyrrole
• CAS NO: 914458-46-1
• Molecular Weight: 451.546
• Mol File: 914458-46-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-phenyl-4-(1-naphthoyl)-N-p-toluenesulfonylpyrrole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-4-(1-naphthoyl)-N-p-toluenesulfonylpyrrole(914458-46-1)
• EPA Substance Registry System: 2-phenyl-4-(1-naphthoyl)-N-p-toluenesulfonylpyrrole(914458-46-1)

Safety Data

• Hazardous Substances Data: 914458-46-1(Hazardous Substances Data)

Upstream product

• 613-91-2 acetophenone oxime 
• 98-59-9 p-toluenesulfonyl chloride 
• 153633-36-4 2-phenyl-1-(p-toluenesulfonyl)pyrrole 
• 879-18-5 naphthalene-1-carbonic acid chloride 
• 3042-22-6 2-phenyl-1H-pyrrole 

Downstream Products

• 914458-21-2 (1-heptyl-5-phenyl-1H-pyrrol-3-yl)-1-naphthalenylmethanone 
• 914458-20-1 (1-hexyl-5-phenyl-1H-pyrrol-3-yl)-1-naphthalenylmethanone 
• 914458-48-3 naphthalen-1-yl(5-phenyl-1H-pyrrol-3-yl)methanone 

Relevant articles and documents

1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: New high affinity ligands for the cannabinoid CB1 and CB2 receptors

Two series of 1-alkyl-2-aryl-4-(1-naphthoyl)pyrroles were synthesized and their affinities for the cannabinoid CB1 and CB2 receptors were determined. In the 2-phenyl series (5) the N-alkyl group was varied from n-propyl to n-heptyl. A second series of 23 1-pentyl-2-aryl-4-(1-naphthoyl)-pyrroles (6) was also prepared. Several compounds in both series have CB1 receptor affinities in the 6-30 nM range. The high affinities of these pyrrole derivatives relative to JWH-030 (1, R = C5H11) support the hypothesis that these pyrroles interact with the CB1 receptor primarily by aromatic stacking.