914637-80-2

Basic information

• Product Name: 4-OXOCYCLOHEXANECARBONYL CHLORIDE
• Synonyms: 4-OXOCYCLOHEXANECARBONYL CHLORIDE
• CAS NO: 914637-80-2
• Molecular Formula: C₇H₉ClO₂
• Molecular Weight: 160.6
• Product Categories: Carbonyl Chlorides;Carbonyl Chlorides;Ring Systems
• Mol File: 914637-80-2.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-OXOCYCLOHEXANECARBONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-OXOCYCLOHEXANECARBONYL CHLORIDE(914637-80-2)
• EPA Substance Registry System: 4-OXOCYCLOHEXANECARBONYL CHLORIDE(914637-80-2)

Safety Data

• Hazardous Substances Data: 914637-80-2(Hazardous Substances Data)

Upstream product

• 17159-79-4 ethyl 4-oxocyclohexane-1-carboxylate 
• 6297-22-9 4-carbomethoxycyclohexanone 
• 874-61-3 4-oxocyclohexanecarboxylic acid 

Downstream Products

• 945843-04-9 2-(trimethylsilyl)ethyl 4-oxocyclohexanecarboxylate 
• 945843-05-0 2-nitrobenzyl 4-oxocyclohexanecarboxylate 
• 897660-91-2 4-oxo-cyclohexanecarboxylic acid methyl-phenyl-amide 
• 1369537-37-0 tert-butyl (2S)-4-{4-[({4-[(4-fluorophenyl)amino]cyclohexyl}carbonyl)(methyl)amino]benzyl}-2-methylpiperazine-1-carboxylate 
• 1369537-36-9 4-[(4-fluorophenyl)amino]-N-methyl-N-(4-{[(3S)-3-methylpiperazin-1-yl]methyl}phenyl)cyclohexanecarboxamide 
• 1369414-28-7 tert-butyl (2S)-2-methyl-4-(4-{methyl[(4-oxocyclohexyl)carbonyl]amino}benzyl)piperazine-1-carboxylate 
• 134924-68-8 2-(4-cis-hydroxycyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino<2,1-a>isoquinolin-4-one 
• 134924-71-3 2-(4-trans-hydroxycyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino<2,1-a>isoquinolin-4-one 
• 945843-33-4 2-nitrobenzyl 15-oxo-7,11,18,21-tetraoxatrispiro[5.2.2.5.2.2]henicosane-3-carboxylate 
• 945843-26-5 2-nitrobenzyl 15-hydroxy-7,11,18,21-tetraoxatrispiro[5.2.2.5.2.2]henicosane-3-carboxylate 
• 945843-17-4 2-nitrobenzyl 15-[(4-methoxybenzyl)oxy]-7,11,18,21-tetraoxatrispiro[5.2.2.5.2.2]henicosane-3-carboxylate 
• 945843-16-3 2-(trimethylsilyl)ethyl 15-[(4-methoxybenzyl)oxy]-7,11,18,21-tetraoxatrispiro[5.2.2.5.2.2]henicosane-3-carboxylate 

Relevant articles and documents

IRAK DEGRADERS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

SUBSTITUTED BICYCLIC COMPOUNDS AS FARNESOID X RECEPTOR MODULATORS

Disclosed are compounds of Formula (I): or a stereoisomer, a tautomer, or a salt or solvate thereof, wherein Q is C2-6 alkenyl or C2-6 alkynyl, each substituted with zero to 2 R1; and the other variables are as defined herein. These compounds modulate the activity of farnesoid X receptor (FXR), for example, as agonists. Also disclosed are pharmaceutical compositions comprising these compounds and methods of treating a disease, disorder, or condition associated with FXR dysregulation, such as pathological fibrosis, transplant rejection, cancer, osteoporosis, and inflammatory disorders, by using the compounds and pharmaceutical compositions.

NOVEL TRICYCLIC COMPOUNDS AS INHIBITORS OF MUTANT IDH ENZYMES

The present invention is directed to tricyclic compounds of formula (I) which are inhibitors of one or more mutant IDH enzymes: (I); wherein A is -C(R1)= or -N=; and X is selected from the group consisting of: (II-i), (II-ii), (II-iii), and (II-iv). The present invention is also directed to uses of the tricyclic compounds described herein in the potential treatment or prevention of cancers in which one or more mutant IDH enzymes are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such cancers.