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57452-32-1

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57452-32-1 Usage

Uses

rac-1,2,3,6,7,11b-Hexahydro-2-[(4-oxocyclohexyl)carbonyl]-4H-pyrazino[2,1-a]isoquinolin-4-one is an analogue of praziquantel (P702095), an anthelmintic that is effective against flatworms.

Check Digit Verification of cas no

The CAS Registry Mumber 57452-32-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,4,5 and 2 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 57452-32:
(7*5)+(6*7)+(5*4)+(4*5)+(3*2)+(2*3)+(1*2)=131
131 % 10 = 1
So 57452-32-1 is a valid CAS Registry Number.

57452-32-1Relevant articles and documents

Development of chiral praziquantel analogues as potential drug candidates with activity to juvenile Schistosoma japonicum

Zheng, Yang,Dong, Lanlan,Hu, Changyan,Zhao, Bo,Yang, Chunhua,Xia, Chaoming,Sun, Dequn

, p. 4223 - 4226 (2014/11/07)

A series of chiral praziquantel analogues were synthesized and evaluated against Schistosoma japonicum both in vitro and in vivo. All compounds exhibited low to considerable good activity in vivo. Remarkably, worm reduction rate of R-3 was 60.0% at a sing

Synthesis and properties of cis- and trans-4-hydroxypraziquantel

Kiec-Kononowicz,Farghaly,Blaschke

, p. 235 - 237 (2007/10/02)

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