91470-28-9

Basic information

• Product Name: 2-Furamide,tetrahydro-(6CI,7CI)
• Synonyms: 2-Furamide,tetrahydro-(6CI,7CI);Tetrahydrofuran-2-carboxaMide;tetrahydro-2-Furancarboxamide;Tetrahydro-furan-2-carboxylic acid amide
• CAS NO: 91470-28-9
• Molecular Formula: C₅H₉NO₂
• Molecular Weight: 115.13046
• Product Categories: AMIDE
• Mol File: 91470-28-9.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-Furamide,tetrahydro-(6CI,7CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Furamide,tetrahydro-(6CI,7CI)(91470-28-9)
• EPA Substance Registry System: 2-Furamide,tetrahydro-(6CI,7CI)(91470-28-9)

Safety Data

• Hazardous Substances Data: 91470-28-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
2-Furamide, tetrahydro-(6CI,7CI) is utilized as a key intermediate in the synthesis of various pharmaceuticals. Its distinctive structure and reactivity contribute to the development of new drugs, enhancing the range of therapeutic options available.
Used in Organic Chemistry:
In the field of organic chemistry, 2-Furamide, tetrahydro-(6CI,7CI) serves as a versatile building block. Its unique properties allow for the creation of a wide array of organic compounds, expanding the scope of chemical research and innovation.
Used in Agrochemicals:
2-Furamide, tetrahydro-(6CI,7CI) also finds applications in the agrochemical industry. Its potential use in the development of new pesticides or other agricultural chemicals could contribute to more effective and sustainable agricultural practices.
Used in Materials Science:
2-Furamide,tetrahydro-(6CI,7CI)'s potential applications extend to materials science, where it may be employed in the development of new materials with specific properties. Further research into its properties and reactivity could uncover additional uses, broadening its impact across various industries.

Upstream product

• 609-38-1 furan-2-carboxylic acid amide 
• 16874-33-2 tetrahydro-2-furancarboxylic acid 
• 541-41-3 chloroformic acid ethyl ester 
• 16874-34-3 ethyl tetrahydrofurancarboxylate 

Downstream Products

• 1191-99-7 2,3-dihydro-2H-furan 
• 14631-43-7 2-tetrahydrofuran-2-carbonitrile 
• 1615-70-9 penta-2,4-dienenitrile 
• 619329-27-0 tetrahydro-2-furancarboximidamide hydrochloride 
• 688000-41-1 tetrahydrofuran-2-carboximidamide 

Relevant articles and documents

Macrocyclic MCL-1 inhibitors and methods of use

The present disclosure provides for compounds of Formula (I) wherein A2, A3, A4, A6, A7, A8, A15, RA, R5, R9, R10A, R10B, R11, R12, R13, R14, R16, W, X, and Y have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents for the treatment of diseases and conditions, including cancer. Also provided are pharmaceutical compositions comprising compounds of Formula (I).

Corresponding amine nitrile and method of manufacturing thereof

The invention relates to a manufacturing method of nitrile. Compared with the prior art, the manufacturing method has the characteristics of significantly reduced using amount of an ammonia source, low environmental pressure, low energy consumption, low production cost, high purity and yield of a nitrile product and the like, and nitrile with a more complex structure can be obtained. The invention also relates to a method for manufacturing corresponding amine from nitrile.

Heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase; The identification of (2R)-2-pyrrolidinecarboxamidine as a potent and selective haem-co-ordinating inhibitor

Heteroalicyclic carboxamidines were synthesised and evaluated as inhibitors of nitric oxide synthases. (2R)-2-Pyrrolidinecarboxamidine, in particular, was shown to be a highly potent in vitro (IC50 = 0.12 μM) and selective iNOS inhibitor (>100-fold vs both eNOS and nNOS), with probable binding to the key anchoring glutamate residue and co-ordination to the haem iron.

Alpha substituted carboxylic acids

Alpha substituted carboxylic acids of formula (I):

ALPHA SUBSTITUTED CARBOXYLIC ACID AS PPAR MODULATORS

Alpha substituted carboxylic acids of formula (I): wherein R' and R2 are as defined in the specification and R3 is A) formula (II); B) formula (III); C) formula (IV); and D) formula (V); wherein Y, Art, Are, AP, R4, R5, R6, R7, R6, R9, R9a, R10, R", R12, R17, ring A, and p are as defined in the specification; pharmaceutical compositions containing effective amounts of said compounds or their salts are useful for treating PPAR, specifically PPAR α/y related disorders, such as diabetes, dyslipidemia, obesity and inflammatory disorders.