91476-81-2 Usage
Uses
Used in Pharmaceutical Industry:
Imidazo[1,2-a]pyrazine-2-carboxylic acid, 5,6,7,8-tetrahydro-, methyl ester (9CI) is used as a synthetic intermediate for the development of histone deacetylase inhibitors. These inhibitors play a crucial role in the regulation of gene expression and are being investigated for their potential therapeutic effects in various diseases, including cancer and neurodegenerative disorders. Imidazo[1,2-a]pyrazine-2-carboxylic acid, 5,6,7,8-tetrahydro-, methyl ester (9CI)'s ability to be incorporated into histone deacetylase inhibitors makes it a valuable tool in the advancement of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 91476-81-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,4,7 and 6 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 91476-81:
(7*9)+(6*1)+(5*4)+(4*7)+(3*6)+(2*8)+(1*1)=152
152 % 10 = 2
So 91476-81-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H11N3O2/c1-13-8(12)6-5-11-3-2-9-4-7(11)10-6/h5,9H,2-4H2,1H3
91476-81-2Relevant academic research and scientific papers
Derives N-nitres et N-nitroses en serie tetrahydro-5,6,7,8 imidazopyrazinique : obtention et determination par RMN 1H des configurations Z et E.
Bonnet, Pierre-Antoine,Sablayrolles, Claire,Chapat, Jean-Pierre
, p. 468 - 480 (2007/10/02)
Les derives N-nitres et N-nitroses en serie tetrahydro-5,6,7,8 imidazopyrazinique sont obtenus simultanement lors de la nitration par HNO3 (d = 1.51) en milieu sulfurique.L'analyse des isomeres N-nitroses Z et E met en evidence l'apparition preponderante de la forme Z ainsi qu'une restriction importante a son equilibration.La stabilite particuliere de l'isomere Z est attribuee a l'existence d'une assistance electronique preferentielle entre groupement nitroso et protons en position 8.
