914922-79-5

Upstream product

• 852204-49-0 (2R,3R,4R,5S,6S)-2-[(acetyloxy)methyl]-6-(4-bromophenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate 
• 73183-34-3 bis(pinacol)diborane 
• 914922-78-4 (1S)-1,5-anhydro-1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-D-glucitol 
• 108-24-7 acetic anhydride 
• 135700-53-7 4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-chlorobenzene 
• 3947-62-4 2,3,4,6-tetraacetylglucose 
• 572-09-8 2,3,4,6-tetra-O-acetyl-D-glucopyranosyl bromide 
• 572-09-8 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide 
• 18620-02-5 (4-bromophenyl)magnesium bromide 
• 106-37-6 1.4-dibromobenzene 
• 83-87-4 D-glucose pentaacetate 

Downstream Products

• 914922-80-8 (1S)-2,3,4,6-tetra-O-acetyl-1,5-anhydro-1-(3'-(benzyloxy)-4'-{(2S,3R)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxo-1-phenylazetidin-2-yl}biphenyl-4-yl)-D-glucitol 

Relevant academic research and scientific papers

Process For Production Of 4-Biphenylyazetidin-2-Ones

The present invention relates to processes for the production of 4-biphenylylazetidin-2-one derivatives of formula

1,4-DIPHENYL-3-HYDROXYALKYL-2-AZETIDINONE DERIVATIVES FOR TREATING HYPERCHOLESTROLEMIA

The invention relates to a chemical genus of 1,4-diphenyl-3-hydroxyalkyl-2-azetidinones useful for the treatment of hypercholesterolemia and related disorders, having general formula (I).

BIPHENYLAZETIDINONE CHOLESTEROL ABSORPTION INHIBITORS

The invention relates to a chemical genus of 4-biphenyl-1-phenylazetidin-2-ones useful in the treatment of hypercholesterolemia and other disorders. The compounds have the general formula (I). Pharmaceutical compositions and methods for treating cholesterol- and lipid-associated diseases are also disclosed.

DIPHENYLHETEROCYCLE CHOLESTEROL ABSORPTION INHIBITORS

Various azetidinone, pyrrolidine, imidazolidine, and oxazolidine derivatives are described, as are pharmaceutical compositions containing these compounds and methods of treatment of diseases using these compounds. Other embodiments are also described.

PHENYLAZETIDINONE DERIVATIVES

Various azetidinone derivatives are described, as are pharmaceutical compositions containing these compounds and methods of treatment of diseases using these compounds. Other embodiments are also described.