91497-39-1

Basic information

• Product Name: ETHOXYCARBONYLMETHYL PHENYLACETATE
• Synonyms: ETHOXYCARBONYLMETHYL PHENYLACETATE;ETHYL (PHENYLACETOXY)ACETATE;ETHYL (PHENYLACETOXY)ACETATE 99%;PHENYLACETOXY ACETIC ACID ETHYL ESTER;2-Ethoxy-2-oxoethyl 2-phenylacetate
• CAS NO: 91497-39-1
• Molecular Formula: C₁₂H₁₄O₄
• Molecular Weight: 222.24
• Mol File: 91497-39-1.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 316.5°C at 760 mmHg
• Flash Point: >230 °F
• Appearance: /
• Density: 1.121 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.00041mmHg at 25°C
• Refractive Index: n20/D 1.497(lit.)
• CAS DataBase Reference: ETHOXYCARBONYLMETHYL PHENYLACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHOXYCARBONYLMETHYL PHENYLACETATE(91497-39-1)
• EPA Substance Registry System: ETHOXYCARBONYLMETHYL PHENYLACETATE(91497-39-1)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 91497-39-1(Hazardous Substances Data)

Usage

General Description

ETHOXYCARBONYLMETHYL PHENYLACETATE is a chemical compound with the molecular formula C13H16O4. It is an ester, formed from the condensation of ethoxycarbonylmethyl chloride with phenylacetic acid. ETHOXYCARBONYLMETHYL PHENYLACETATE is commonly used in organic synthesis and as a reagent in the preparation of various pharmaceuticals and other organic molecules. It is a colorless liquid with a slight aromatic odor and is stable under normal conditions. ETHOXYCARBONYLMETHYL PHENYLACETATE is primarily used as an intermediate in the production of other chemicals and does not have any known significant toxicological effects.

InChI:InChI=1/C12H14O4/c1-2-15-12(14)9-16-11(13)8-10-6-4-3-5-7-10/h3-7H,2,8-9H2,1H3

Upstream product

• 623-50-7 ethyl 2-hydroxyacetate 
• 103-80-0 phenylacetyl chloride 
• 623-73-4 diazoacetic acid ethyl ester 
• 101-97-3 Ethyl 2-phenylethanoate 
• 114-70-5 sodium phenylacetate 
• 105-36-2 ethyl bromoacetate 
• 103-82-2 phenylacetic acid 
• 105-39-5 chloroacetic acid ethyl ester 

Downstream Products

• 23782-85-6 3-phenyltetronic acid 
• 1421237-03-7 C₁₈H₁₆O₄ 
• 100074-92-8 4-methoxy-3-phenyl-5-(phenylmethylene)furan-2(5H)-one 
• 78376-10-0 (Z)-5-benzylidene-4-hydroxy-3-phenylfuran-2(5H)-one 
• 1421237-20-8 C₂₂H₂₂FNO₅ 
• 1421237-28-6 C₂₂H₂₀FNO₄ 
• 1421237-30-0 C₂₂H₂₀FNO₄ 
• 1514776-24-9 7-(4-(2-(3-phenylfuran-2(5H)-one-4-yloxy)ethyl)piperazin-1-yl)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 
• 1514776-33-0 7-(4-(2-(3-phenylfuran-2(5H)-one-4-yloxy)ethyl)piperazin-1-yl)-1-ethyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid 
• 1514776-29-4 7-(4-(2-(3-phenylfuran-2(5H)-one-4-yloxy)ethyl)piperazin-1-yl)-1-(4-fluorophenyl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 
• 1514776-26-1 7-(4-(2-(3-phenylfuran-2(5H)-one-4-yloxy)ethyl)piperazin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 
• 1450824-55-1 4-(2-(3,4-dimethoxyphenylacetyloxyl)ethoxy)-3-phenylfuran-2(5H)-one 
• 1450824-52-8 4-(2-(4-fluorophenylacetyloxyl)ethoxy)-3-phenylfuran-2(5H)-one 
• 1450824-50-6 4-(2-(3,5-dihydroxyphenylformyloxyl)ethoxy)-3-phenylfuran-2(5H)-one 

Relevant articles and documents

Compound, as well as preparation method and application thereof

The application discloses a compound of which the structure is represented as the following formula, wherein R1 is selected from any one of F, Cl, Br, C1-C5 alkyl group, and a group having the structure as the formula (1), n = 0, 1, 2, 3, 4 or 5; the R2 is selected from any one of a group having the structure as the formula (1), a group having the structure as the formula (2), and a group having the structure as the formula (3). The compound has simple preparation method, can be used as a neuraminidase inhibitor, and has excellent antivirus activity.

Silver-catalyzed functionalization of esters by carbene transfer: The role of ylide zwitterionic intermediates

The reaction of esters with ethyl diazoacetate catalyzed by the complex [F27-Tp4Bo,3CF2CF3Ag(acetone)] generates α-(acyloxy)acetates in moderate to high yields. This is a novel transformation in the context of carbene-transfer reactions from diazo compounds that, according to experimental and theoretical data, is suggested to occur through zwitterionic intermediates.

A facile synthesis, antibacterial activity of pulvinone and its derivatives

Pulvinone and several 3-fluoro-4-morpholino substituted pulvinone derivatives were synthesized in five steps from a common precursor, phenyl acetic acid. Most of synthetic morpholine substituted pulvinones showed inhibitory activity against Esherichia col