915141-52-5

Upstream product

• 915141-50-3 (3S,4R,5R)-6-(tert-Butyl-dimethyl-silanyloxy)-4-(4-methoxy-benzyloxy)-3,5-dimethyl-hexan-2-one 
• 75-77-4 chloro-trimethyl-silane 
• 151058-21-8 (+)-[2S-(2R*,3S*,4S*)]-5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-[(4-methoxyphenyl)methoxy]-N-methoxy-N-2,4-trimethylpentanamide 

Downstream Products

• 915141-66-1 (2R,5S,6R,7R)-1-[(2S,4S,6S)-6-(3-Benzyloxy-propyl)-2-phenyl-[1,3]dioxan-4-yl]-2,8-bis-(tert-butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-5,7-dimethyl-octan-4-one 
• 915141-54-7 (2R,5S,6R,7R)-1-[(2S,4R,6S)-6-(3-Benzyloxy-propyl)-2-phenyl-[1,3]dioxan-4-yl]-8-(tert-butyl-dimethyl-silanyloxy)-2-hydroxy-6-(4-methoxy-benzyloxy)-5,7-dimethyl-octan-4-one 

Relevant academic research and scientific papers

Enantioselective synthesis of the C1-C15 fragment of dolabelide C

A synthesis of the C1-C15 fragment of dolabelide C is reported. The key step is a diastereoselective Mukaiyama aldol reaction to form the C6-C7 bond, followed by reduction and deoxygenation of the carbonyl group at C5. The trisubstituted vinyl iodide is i