915150-33-3Relevant academic research and scientific papers
Synthesis of the essential core of the human glycosylphosphatidylinositol (GPI) anchor
Richichi, Barbara,Luzzatto, Lucio,Notaro, Rosario,Marca, Giancarlo La,Nativi, Cristina
, p. 88 - 93 (2011/05/12)
The biological role of GPI anchors is of paramount importance; however, we are still far from fully understanding the structure-function relationship of these molecules. One major limiting factor has been the tiny quantities available from natural sources
Synthesis of a core arabinomannan oligosaccharide of Mycobacterium tuberculosis
Hoelemann, Alexandra,Stocker, Bridget L.,Seeberger, Peter H.
, p. 8071 - 8088 (2007/10/03)
The synthesis of a core arabinomannan (AM) oligosaccharide from Mycobacterium tuberculosis has been achieved using a convergent [6 + 6] glycosylation strategy and a defined set of building blocks. Dodecasaccharide 1, containing the key AM structural featu
Total synthesis of phosphatidylinositol mannosides of Mycobacterium tuberculosis
Liu, Xinyu,Stocker, Bridget L.,Seeberger, Peter H.
, p. 3638 - 3648 (2007/10/03)
The total synthesis of phosphatidylinositol mannosides (PIMs), a key class of antigenic glycolipids found on the cell wall of Mycobacterium tuberculosis, is described. The synthetic strategy relied on a [4 + 3] glycosylation of tetramannoside 1 and pseudo
