915150-33-3Relevant academic research and scientific papers
Synthesis of the essential core of the human glycosylphosphatidylinositol (GPI) anchor
Richichi, Barbara,Luzzatto, Lucio,Notaro, Rosario,Marca, Giancarlo La,Nativi, Cristina
, p. 88 - 93 (2011/05/12)
The biological role of GPI anchors is of paramount importance; however, we are still far from fully understanding the structure-function relationship of these molecules. One major limiting factor has been the tiny quantities available from natural sources
Total synthesis of phosphatidylinositol mannosides of Mycobacterium tuberculosis
Liu, Xinyu,Stocker, Bridget L.,Seeberger, Peter H.
, p. 3638 - 3648 (2007/10/03)
The total synthesis of phosphatidylinositol mannosides (PIMs), a key class of antigenic glycolipids found on the cell wall of Mycobacterium tuberculosis, is described. The synthetic strategy relied on a [4 + 3] glycosylation of tetramannoside 1 and pseudo
Synthesis of a core arabinomannan oligosaccharide of Mycobacterium tuberculosis
Hoelemann, Alexandra,Stocker, Bridget L.,Seeberger, Peter H.
, p. 8071 - 8088 (2007/10/03)
The synthesis of a core arabinomannan (AM) oligosaccharide from Mycobacterium tuberculosis has been achieved using a convergent [6 + 6] glycosylation strategy and a defined set of building blocks. Dodecasaccharide 1, containing the key AM structural featu
