91534-13-3Relevant academic research and scientific papers
A Stereocontrolled Route to the Tricyclo3,8>pentadecane Ring System of Taxane
Brown, Paul A.,Jenkins, Paul R.,Fawcett, John,Russell, David R.
, p. 253 - 255 (1984)
The synthesis of a tricyclo3,8>pentadecane system which has the same relative stereochemistry about its chiral centres as the taxane natural products is reported.
A Convergent Approach to the Taxane Class of Compounds
Funk, Raymond L.,Daily, William J.,Parvez, M.
, p. 4141 - 4143 (2007/10/02)
A short A + C -> AC -> ABC route to the taxane class of compounds is described which features a Claisen-rearrangements-mediated stereocontrolled ring closure of the central eight-membered ring in the key AC -> ABC step.
Synthesis of the Taxane Ring System using an Intramolecular Diels-Alder Reaction of a 2-Substituted Diene
Brown, Paul A.,Jenkins, Paul R.
, p. 1303 - 1310 (2007/10/02)
A synthesis of (1R/S,3R/S,8S/R)-8-methyltricyclopentadec-11-en-2-one, which is the ring system of the taxane natural products and contains 3 chiral centres having the required relative configuration, is described.
