915401-65-9Relevant academic research and scientific papers
5-(2-Pyrrolidinyl)oxazolidinones and 2-(2-pyrrolidinyl)benzodioxanes: Synthesis of all the stereoisomers and α4β2 nicotinic affinity
Pallavicini, Marco,Bolchi, Cristiano,Binda, Matteo,Cilia, Antonio,Clementi, Francesco,Ferrara, Rossana,Fumagalli, Laura,Gotti, Cecilia,Moretti, Milena,Pedretti, Alessandro,Vistoli, Giulio,Valoti, Ermanno
scheme or table, p. 854 - 859 (2009/08/15)
The four stereoisomers of 2-oxazolidinone 5-substituted with 1-methyl-2-pyrrolidinyl (1), of 1,4-benzodioxane 2-substituted with the same residue (2) and of the nor-methyl analogue of this latter (2a) were synthesized as candidate nicotinoids. Of the 12 c
Synthesis and α4β2 nicotinic affinity of unichiral 5-(2-pyrrolidinyl)oxazolidinones and 2-(2-pyrrolidinyl)benzodioxanes
Pallavicini, Marco,Moroni, Barbara,Bolchi, Cristiano,Cilia, Antonio,Clementi, Francesco,Fumagalli, Laura,Gotti, Cecilia,Meneghetti, Fiorella,Riganti, Loredana,Vistoli, Giulio,Valoti, Ermanno
, p. 5610 - 5615 (2007/10/03)
The RS and SR enantiomers of 2-oxazolidinone and 1,4-benzodioxane bearing a 2-pyrrolidinyl substituent at the 5- and 2-position, respectively, were synthesized as candidate nicotinoids. One of the two benzodioxane stereoisomers reasonably fits the pharmac
