91545-47-0Relevant academic research and scientific papers
Direction of alkylation of 5-aryl-1,3,4-oxadiazoline-2-thiones
Ziyaev,Galust'yan
, p. 1109 - 1111 (1997)
The reaction of potassium salt of 5-(2,4-dichlorophenyl)-1,3,4-oxadiazoline-2-thione with dimethyl sulfate was carried out in water and HMPT. It was shown that the nature of the solvent affects the ratio of the formed products of S- and N-methylation. The alkylation of 5-aryl-1,3,4-oxadiazoline-2-thiones with isomeric butyl chlorides showed that the reaction takes place only with n-butyl chloride with the formation of the corresponding S-butyl-substituted derivative. 1998 Plenum Publishing Corporation.
METHYLATION OF 5-ARYL-1,3,4-OXADIAZOLINE-2-THIONES
Ziyaev, A. A.,Galust'yan, G. G.,Sabirov, K.,Nasirov, S.,Tashkhodzhaev, B.,Yagudaev, M. R.
, p. 1221 - 1225 (2007/10/02)
The methylation of 5-aryl-1,3,4-oxadiazoline-2-thiones in various solvents in the range of 56-81 deg C leads to the formation of S-methyl derivatives and to insignificant formation of N-methyl derivatives.
Synthesis and Biological Activity of Some New 3-Substituted 5-(2,4-Dichlorophenyl)-1,3,4-oxadiazole-2-thiones
Goswami, B. N.,Kataky, J. C. S.,Baruah, J. N.
, p. 796 - 797 (2007/10/02)
A series of 3-arylaminomethyl-5-(2,4-dichlorophenyl)-1,3,4-oxadiazole-2-thiones (4a-19a) and 3-alkyl/aralkyl-5-(2,4-dichlorophenyl)-1,3,4-oxadiazole-2-thiones (4b-9b) have been synthesised and screened for their biological activities.Some of the compounds
