91550-13-9

Upstream product

• 138053-02-8 (4R,5S)-3-((R)-4-Benzyloxy-2-methyl-butyryl)-4-methyl-5-phenyl-oxazolidin-2-one 
• 138053-01-7 (4R,5S)-3-(4-Benzyloxy-butyryl)-4-methyl-5-phenyl-oxazolidin-2-one 
• 33857-76-0 Boc-proline 2-thiopyridyl ester 
• 91550-08-2 (S)-2-acetylpyrrolidine-1-carboxylic acid tert-butyl ester 
• 96154-47-1 (R)-2-methyl-1,4-butanediol 4-benzyl ether 
• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 
• 91550-05-9 (8R,8_αS)-8-hydroxy-8-methyl-7-octahydroindolizidone 
• 91550-10-6 (8R,8aS)-7-Methoxy-8-hydroxy-8-methyl-1,2,3,5,8,8a-hexahydroindolizine 
• 91550-09-3 (R)-α-Methyl-α-(1-methoxypropadienyl)-2(S)-pyrrolidinemethanol 
• 91550-14-0 (2R)-4-(Benzyloxy)-2-methyl-1-butanal 

Downstream Products

• 91550-04-8 (+)-Allopumiliotoxin 339B 
• 91550-15-1 (8R,8aS)-7-<<(Dimethylethyl)dimethylsilyl>oxy>-8-hydroxy-8-methyl-6-<(Z)-2(R)-methyl-4-(benzyloxy)butylidene>octahydroindolizine 
• 91550-17-3 (8R,8aS)-7-<<(Dimethylethyl)dimethylsilyl>oxy>-8-hydroxy-8-methyl-6-<(Z)-2(R),5-dimethyl-7-<<(dimethylethyl)diphenylsilyl>oxy>-6-oxo-4-octen-1-ylidene>octahydroindolizine 
• 138053-03-9 (8R,8aS)-8-Hydroxy-8-methyl-6-<(Z)-2(R)-methyl-4-(benzyloxy)butylidene>octahydroindolizin-7-ol 

Relevant academic research and scientific papers

The First Enantioselectice Total Syntheses of the Allopumiliotoxin A Alkaloids 267A and 339B

Short, highly stereocontrolled, asymmetric total syntheses of the title amphibian alkaloids are described.In the first stage the indolizidine ketone 11 is assembled from L-proline in enantiomerically pure form.This short sequence proceeds in five laborato