91552-24-8

Basic information

• Product Name: 2-(3-chlorophenyl)-5,6-dihydro-4H-1,3-oxazine
• Synonyms: 2-(3-chlorophenyl)-5,6-dihydro-4H-1,3-oxazine
• CAS NO: 91552-24-8
• Molecular Weight: 195.648
• Mol File: 91552-24-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(3-chlorophenyl)-5,6-dihydro-4H-1,3-oxazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-chlorophenyl)-5,6-dihydro-4H-1,3-oxazine(91552-24-8)
• EPA Substance Registry System: 2-(3-chlorophenyl)-5,6-dihydro-4H-1,3-oxazine(91552-24-8)

Safety Data

• Hazardous Substances Data: 91552-24-8(Hazardous Substances Data)

Upstream product

• 766-84-7 3-chloro-benzonitrile 
• 156-87-6 propan-1-ol-3-amine 

Relevant articles and documents

A green and selective synthesis of 2-aryloxazines and 2- aryltetrahydropyrimidines

An efficient method for the selective synthesis of 2-substituted oxazines and tetrahydropyrimidines by the reaction of arylnitriles with 3-amino-1-propanol and 1,3-diaminopropane in the presence of montmorillonite K-10 and KSF as inexpensive, environmenta

H3PW12O40: An efficient and recyclable heterogeneous catalyst for the selective synthesis of 2-Aryl-5,6-dihydro-4H-1,3- oxazines and 2-Aryl-1,4,5,6-tetrahydropyrimidines

An environmentally friendly and highly efficient procedure has been developed for the selective synthesis of 2-aryl-5,6-dihydro-4H-1,3-oxazines and 2-aryl-1,4,5,6-tetrahydropyrimidines by cyclocondensation of arylnitriles with 3-amino-1-propanol and 1,3-diaminopropane in the presence of catalytic amounts of H3PW12O40 under thermal conditions and MW irradiation. Under the same reaction conditions, dicyanobenzenes are transformed to their corresponding mono-oxazines and monotetrahydropyrimidines with excellent chemoselectivity. These reactions are simple and clean, giving the products in high yields and high purity. The catalyst can be easily recovered after the reaction and reused efficiently in subsequent runs.