91574-45-7

Usage

Uses

Used in Pharmaceutical Industry:
Benzeneacetic acid, 4-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)is utilized as a therapeutic agent for the treatment of neurological disorders, specifically attention deficit hyperactivity disorder (ADHD) and narcolepsy. Its efficacy is attributed to its dopamine-modulating properties, which help in managing the symptoms of these conditions by improving focus, attention, and wakefulness.
Used in Research Applications:
In the field of scientific research, Benzeneacetic acid, 4-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)serves as a valuable compound for studying the effects of dopamine reuptake inhibition on cognitive functions and memory enhancement. This research can contribute to the development of new treatments for various cognitive disorders and a better understanding of the role of dopamine in brain function.

Upstream product

• 108-31-6 maleic anhydride 
• 1197-55-3 4-aminophenylacetic acid 
• 188985-07-1 (Z)-3-(4-Carboxymethyl-phenylcarbamoyl)-acrylic acid 

Downstream Products

• 697238-48-5 [4-(6,5-dioxo-6,5-dihydro-pyrrol-4-yl)-phenyl]acetic acid methyl ester 
• 91574-33-3 4-maleimidophenylacetic acid NHS ester 
• 188985-11-7 N'-{2-[4-(2,5-Dioxo-2,5-dihydro-pyrrol-1-yl)-phenyl]-acetyl}-hydrazinecarboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Amide compounds for regulating WNT signal channel and application of compounds

The invention belongs to the technical field of medicine, and particularly relates to amide compounds for regulating a WNT signal channel and an application of the compounds. The compounds have a structure represented by a general formula I shown in the description.

Stabilization of cysteine-linked antibody drug conjugates with N-aryl maleimides

Maleimides are often used to covalently attach drugs to cysteine thiols for production of antibody-drug conjugates (ADCs). However, ADCs formed with traditional N-alkyl maleimides have variable stability in the bloodstream leading to loss of drug. Here, w

A simple synthetic replicator amplifies itself from a dynamic reagent pool

(Figure Presented) The fate of a dynamic combinatorial library is determined by coupling the exchange processes to a synthetic replicator. The replicating template is capable of exploiting and dominating the exchanging pool of reagents in order to amplify

Design and implementation of a highly selective minimal self-replicating system

Self-direction: A rationally designed self-complementary template (see picture) is capable of replication, thereby amplifying itself from a reaction mixture to the exclusion of its diastereomer. This approach allows a highly selective amplification by foc

Synthesis of New Bifunctional Maleimide Compounds for the Preparation of Chemoimmunoconjugates

Bifunctional maleimide compounds are suitable for binding small molecules to carrier proteins in that they bind to the sulfhydryl group of proteins through the double bond of the maleimide group and to molecules of low molecular weight (e.g. anticancer drugs) through a functional group X. 18 maleimide compounds of the general formula Maleimid-R-X (R = phenylene, benzyl-, methylene-, ethylene, or a m-benzoylethylamide group and X = hydroxy-, amino-, hydrazino-, carboxylic acid-, carboxylic anhydride-, carboxylic acid chloride-, carboxylic acid hydrazide-, oxycarbonylchloride-, aldehyde, keto-, or p-toluenesulfonate-group) were synthesized and characterized through 1H- and 13C-NMR-spectroscopy, elemental analysis, and mass spectrometry.