91574-33-3 Usage
Chemical structure
1H-Pyrrole-2,5-dione, 1-[4-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]phenyl]
Type of compound
chemical compound
Use
scientific research as a specific inhibitor of the enzyme cyclooxygenase-1 (COX-1)
Role of COX-1
involved in the synthesis of prostaglandins and thromboxane, which are important in various physiological processes such as inflammation, pain, and fever
Therapeutic potential
treatment of inflammatory and pain-related conditions
Additional research
studied for its potential use in cancer research, as it may have anti-proliferative and anti-angiogenic effects
Limitations
further research is needed to fully understand the potential benefits and limitations of 1H-Pyrrole-2,5-dione,
1-[4-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]phenyl]- in various medical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 91574-33-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,5,7 and 4 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 91574-33:
(7*9)+(6*1)+(5*5)+(4*7)+(3*4)+(2*3)+(1*3)=143
143 % 10 = 3
So 91574-33-3 is a valid CAS Registry Number.
91574-33-3Relevant academic research and scientific papers
Christie, R. James,Fleming, Ryan,Bezabeh, Binyam,Woods, Rob,Mao, Shenlan,Harper, Jay,Joseph, Augustine,Wang, Qianli,Xu, Ze-Qi,Wu, Herren,Gao, Changshou,Dimasi, Nazzareno
, p. 660 - 670 (2015)
Maleimides are often used to covalently attach drugs to cysteine thiols for production of antibody-drug conjugates (ADCs). However, ADCs formed with traditional N-alkyl maleimides have variable stability in the bloodstream leading to loss of drug. Here, w
