91575-96-1Relevant academic research and scientific papers
A Stereoconvergent Synthesis of (+)-4-Demethoxydaunomycin
Rao, A. V. Rama,Yadav, J. S.,Reddy, K. Bal,Mehendale, A. R.
, p. 453 - 455 (2007/10/02)
Sharpless kinetic asymmetric epoxidation on (+/-)-2-(1-hydroxyethyl)-5,8-dimethoxy-3,4-dihydronaphthalene followed by LiAlH4 reduction gave R-(-)-2-(S-1-hydroxyethyl)-2-hydroxy-5,8-dimethoxy-1,2,3,4-tetrahydronaphthalene and the undesired antipode: the former was converted into R-(-)-2-acetyl-2-hydroxy-5,8-dimethoxy-1,2,3,4-tetrahydronaphthalene while the latter was epimerized and recycled.
