55077-80-0

Basic information

• Product Name: 5,8-dimethoxy-1,2-dihydronaphthalene
• CAS NO: 55077-80-0
• Molecular Formula: C₁₂H₁₄O₂
• Molecular Weight: 190.2384
• Mol File: 55077-80-0.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 330.8°C at 760 mmHg
• Flash Point: 140.7°C
• Density: 1.071g/cm³
• Vapor Pressure: 0.000312mmHg at 25°C
• Refractive Index: 1.543
• CAS DataBase Reference: 5,8-dimethoxy-1,2-dihydronaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 5,8-dimethoxy-1,2-dihydronaphthalene(55077-80-0)
• EPA Substance Registry System: 5,8-dimethoxy-1,2-dihydronaphthalene(55077-80-0)

Safety Data

• Hazardous Substances Data: 55077-80-0(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 55077-79-7 5,8-dimethoxy-1,4-dihydronaphthalene 
• 124-41-4 sodium methylate 
• 130-15-4 [1,4]naphthoquinone 
• 1015-55-0 5,8-dimethoxytetralone 
• 10075-62-4 1,4-dimethoxynaphthalene 
• 35043-92-6 cis-5,8,9,10-tetrahydronaphtho-1,4-quinone 
• 83514-33-4 1,4-Dihydroxy-5,6-dihydronaphthalene 
• 77-78-1 dimethyl sulfate 
• 4676-60-2 5,8-dimethoxy-1,2,3,4-tetrahydro-2H-1-naphthalenol 

Downstream Products

• 10075-62-4 1,4-dimethoxynaphthalene 
• 37464-90-7 5,8-dimethoxy-2-tetralone 
• 33628-85-2 (+/-)-2-acetyl-2-hydroxy-1,2,3,4-tetrahydro-5,8-dimethoxynaphthalene 
• 91575-96-1 Benzoic acid (S)-1-(5,8-dimethoxy-3,4-dihydro-naphthalen-2-yl)-ethyl ester 
• 75251-98-8 2-acetyl-5,8-dimethoxy-3,4-dihydronaphthalene 
• 41098-96-8 (R)-2-acetyl-2-hydroxy-5,8-dimethoxy-1,2,3,4-tetrahydronaphthalene 
• 74526-84-4 1,2,3,4-tetrahydro-5,8-dimethoxynaphthalene 

Relevant articles and documents

Simple and efficient synthesis of 4,7-dimethoxy-1(H)-indene

Stirring 4,7-dimethoxy-1-indanol in chloroform at room temperature in the presence of a catalytic amount of p-toluenesulfonic acid gave 4,7-dimethoxy-1(H)-indene in quantitative yield. Other solvents, including benzene, which was the most frequently used one for this reaction, gave mostly polymeric materials. The new method was also effective for dehydration of other electron-rich benzylic alcohols. Copyright Taylor & Francis Group, LLC.

Simple Preparation of β-Tetralones and β-Indanones by a 1,2-Carbonyl Group Transposition

By a four-step procedure, the ketones 3 are converted into the β-tetralones 7a-d and the β-indanones 7e, f via the intermediates 4, 5, and 6.

A Stereoconvergent Synthesis of (+)-4-Demethoxydaunomycin

Sharpless kinetic asymmetric epoxidation on (+/-)-2-(1-hydroxyethyl)-5,8-dimethoxy-3,4-dihydronaphthalene followed by LiAlH4 reduction gave R-(-)-2-(S-1-hydroxyethyl)-2-hydroxy-5,8-dimethoxy-1,2,3,4-tetrahydronaphthalene and the undesired antipode: the former was converted into R-(-)-2-acetyl-2-hydroxy-5,8-dimethoxy-1,2,3,4-tetrahydronaphthalene while the latter was epimerized and recycled.